Supplemental Figure 3: gating strategy for isolating the lymphocyte population from CD4+CD25+
T lymphocyte subpopulation, purified on magnetic beads, for Figure 3.
We found an elevated rate of CD122-expressing cells among the CD4+
T lymphocyte population in PE compared with HP.
Laboratory control values for CD4 and CD8
T lymphocytes. Implications for HIV-1 diagnosis.
Studies have shown that ROS play an important role in
T lymphocyte proliferation.
The most important effectors of the cell-mediated immune response, cytotoxic
T lymphocytes, are the main immune cells that recognize foreign antigens on the surface of infected "self" cells.
Cytotoxic
T lymphocyte antigen-4 (CTLA-4, CD152) blocks the production of IL-2, the expression of IL-2R, and the cell cycle of activated
T lymphocytes [28].
In fact, although oxidative phosphorylation still occurs in effector
T lymphocytes [8], it seems that, of the glutamine (and glucose) utilized by these cells, only approximately 1.5% is oxidized [3].
Induction of cytotoxic
T lymphocyte development from murine thymocytes by IL-1 and IL-6.
Primary induction of human CD8+ cytotoxic
T lymphocytes and interferon-gamma-producing T cells after smallpox vaccination.
Rotavirus-specific cytotoxic
T lymphocytes appear at the intestinal mucosal surface after rotavirus infection.
All the volunteers had
T lymphocyte counts in the normal or near-normal range, a sign that the virus had yet to gain an edge on the immune system.
T lymphocytes, especially [CD4.sup.+], play important role in wound healing by secreting lymphokines to activate fibroblast, as wound anti-inflammatory agent, and activate factor in major histocompatibility complex (MHC) class II.