T cell

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Related to T-cells: Cytokines, B-cells

T cell

[′tē ‚sel]
(immunology)
One of a heterogeneous population of thymus-derived lymphocytes which participates in the immune responses. Also known as T lymphocyte.
References in periodicals archive ?
The minibodies are linked to Zirconium-89, illuminating CD8 T-cells to provide a whole-body picture of immune response.
Killer T-cells are an important component of our immune system.
For HIV, lack of memory T-cells prevents the so-called "hiding place" or reservoir to avoid interaction with antiretroviral drugs.
In Japan, patent 5244610, titled "Improved method for expansion of tumour-reactive T-lymphocytes for immunotherapy in cancer" covers the process of ex vivo cultivation and activation of CD4+ T-cells.
Professor Mark Peakman, from the National Institute for Health Research Biomedical Research Centre at King's College London and co-author of the study, said: "This first sight of how killer T-cells make contact with the cells that make insulin is very enlightening and increases our understanding of how Type 1 diabetes may arise.
Scientists found a synthetic chemical similar to TNF caused "killer" T-cells in diabetics and patients with other autoimmune conditions to self-destruct.
Activation of T-cells is mediated through two critical signals provided by activated macrophages that play an important role in prompting the protective immune response of Th-1 type against M.
The scientists envisage using one of the lightsensitive antibodies for the T-cell half of the complex.
It has been well established in the scientific literature that at least two signals are required for T-cell activation and that, if only one signal is supplied to T-cells without the ability of the same T-cells to receive a second activation signal, these T-cells undergo "programmed cell death.
National Institute of Allergy and Infectious Diseases (NIAID) reported that an experimental vaccine clearly improved the survival of monkeys after infection by SIV (simian immunodeficiency virus), a virus similar to HIV--even though it did not prevent infection, and did not much improve viral load or total T-cell count.
We made ultrastructural observations and compared human blood monocyte-derived macrophages (MDMs; known to avidly phagocytize PM) with human T-cells (as nonphagocytic controls) on exposure to C or C/Fe particulates.