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In cholestatic hepatitis, serum TBIL and DBIL are regarded as the sensitive diagnosis indices of cholestatic hepatitis, meanwhile, ALT and AST represent the liver function along with disease.
No statistically significant differences in age, sex, educational years, etiology of cirrhosis, Child-Pugh grading, Cr, TBil, ALB, and PT (P > 0.05) were observed, while there were significant differences in Child-Pugh scores (0.009) and ammonia (P < 0.001) in all groups before treatment (Table 2).
Collinearity diagnostics (a) Model Dimension Eigenvalue Condition index 1 1 2.972 1.000 2 0.845 1.876 3 0.177 4.103 4 0.007 20.484 Variance proportions Model Dimension (Constant) Tbil ALB PT 1 1 0.00 0.02 0.00 0.02 2 0.00 0.01 0.00 0.97 3 0.01 0.91 0.02 0.00 4 0.99 0.06 0.98 0.01 (a) Dependent variable: Child-Pugh.
At the same time, TBIL in the Lactobacillus group and Bacillus group was lower than the control group, and the difference was significant (P<0.05, P<0.01).
The preoperative ALT, AST, and TBIL levels were 34.81 [+ or -] 11.81 U/L, 40.12 [+ or -] 25.12 U/L, and 18.21 [+ or -] 10.94 [micro]mol/L, respectively.
Likewise, the mean values of AST, ALT, ALP, TP and TBIL were significantly decreased towards normalcy as observed in healthy buffaloes (p[less than or equal to]0.05).
For the ALP and TBIL levels, a significant difference was seen among all groups (p<0.001) (Figure 1).
A diet supplemented with AFB1+OTA+ZEA significantly (p< 0.05) increased ALT and ALP activities, and TBIL concentration in serum, but there were no significant differences between the other treatments and the control group (Table 4).
Other than ALT, AST, and ALP, change of TBil is the primary laboratory indicator for determining the presence of liver damage and diagnosing DILI.
Total bilirubin (TBIL) was less than or equal to 2 mg/dl in group A and greater than 2 mg/dl in group B.
The serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and total bilirubin (TBIL) levels were assayed using a fully automated Aeroset chemistry analyzer provided by Abbott Co.