Among the 155 CLIA positive, 34 (21.93%) were reactive by RPR of which 32 (20.64%) were confirmed positive by TPHA
The agreement between TPHA
and ELISA tests was nearly perfect with a kappa value of 0.96 (Table 3).
The lowest s/co ratio where TPHA
was positive was 3.1 and below that all samples were negative.
Herring et al,17 evalu-ated nine rapid syphilis ICT kits and reported their sensitivity ranging from 84.5 to 97.7% and specificity from 93 - 98% when compared against TPHA
or T.pallidum particle agglutination (TPPA) as reference method/gold standard.
Due to the possibility of a false positive result caused by a viral infection, tuberculosis, or connective tissue diseases, confirmatory testing with fluorescent treponemal antibody absorption (FTA-ABS) or a Treponema pallidum hemagglutination assay (TPHA
) is necessary.
I have therefore, a while ago, suggested to the board that TPHA
, the Tanzanian Professional Hunters' Association, could create an independent big anti-poaching team, to satellite all the hunting areas of Tanzania.
In the meantime, the serological tests showed a positive venereal disease research laboratory test (VDRL: 1/8) and Treponema Pallidum haemagglutination assay (TPHA
Bir tarama testi olan VDRL testine ilave olarak taniyi dogrulamak icin yapilan TPHA
testinin sonucu da pozitif idi.
The goal of this study was to compare two commercially available total antibody treponemal assays: a conventional TPHA
test with an automated CIA run on the random access Siemens Immulite[R] 2000 analyzer.
The common tests for positive diagnosis are serological, and they include nontreponemal tests (lipoidal antigen tests): flocculation tests (VDRL, RPR); complement fixation tests (RBW, Kolmer), and specific tests (Treponemal): FTA-abs, TPHA
, MHA-TP, TPPA, EIA/IgG (e.g.
Enterovirus) Neurosyphilis VDRL and TPHA
or FTA tests Herpesvirus meningoencephalitis Viral PCR (e.g.