thiamine pyrophosphate

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thiamine pyrophosphate:

see coenzymecoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
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; vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
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The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Thiamine Pyrophosphate


(also cocarboxylase), a coenzyme that participates in the enzymic transformations of α-keto acids and keto sugars; it is present in all animal and plant tissues, as well as in microorganisms.

The catalytic activity of thiamine pyrophosphate is associated with ionization of the carbon atom in the second position of the thiazole ring, to which a molecule of a substrate attaches itself. In industry, thiamine pyrophosphate is obtained from thiamine and pyrophosphoric acid. (For the medical use of thiamine pyrophosphate, SeeCOCARBOXYLASE.)


Kokarboksilaza i drugie tiaminfosfaty. Minsk, 1974.
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.

thiamine pyrophosphate

[′thī·ə·mən ¦pī·rō′fä‚sfāt]
The coenzyme or prosthetic component of carboxylase; catalyzes decarboxylation of various α-keto acids. Also known as cocarboxylase.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Speaking on the same program, Fordham Law Professor Matthew Gold elaborated how Trump's "big win" in regard to the USMCA/NAFTA renegotiations with Canada comes directly from the TPP.
Within this TPP value-added literature, two sets of findings related to model covariates and isolating TPP impacts have implications for the present study: First, regarding the influence of school characteristics, Mihaly, McCaffrey, Sass, and Lockwood (2013) found that aspects of K-12 school context affect TPP value-added estimates.
It is understood that the UK will only be able to join the TPP if it leaves the EU's Customs Union.
Of course, the US membership in the TPP could have steamed ahead faster had Trump decided to return to the pact in its original form from which he had withdrawn.
The TPP aims to eliminate tariffs on industrial and farm products across a bloc whose trade totaled $356 billion last year.
* Encourage small and medium size enterprises (SME) to benefit from TPP opportunities.
Less scrupulous sources use their audience's lack of understanding of these subjects to promulgate rumors and speculation on the TPP's negative impact on the daily lives of U.S.
"Specifically, as a candidate, Trump had argued that TPP was a 'bad deal' because it would cost American blue collar workers their jobs," Rich explained.
During the recent presidential elections, the TPP one of the topics of which both candidates had similar views.
The Philippines is not among the 12 original signatories to the then America-led TPP, but it had been advised to sign up along with countries like Thailand and Indonesia.
With TPP on life support, China promotes two other trade agreements for the region, either of which could exclude the United States and reduce its competitiveness in the Asia Pacific region.
After Trump's victory, Asia Pacific states are turning their focus to the Regional Comprehensive Economic Partnership (RCEP), long viewed as a rival deal to the Trans-Pacific Partnership (TPP) which the New York property billionaire has killed.