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Any of various beta globulins in blood serum which bind and transport iron to the bone marrow and storage areas.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



(also siderophilin), any of a group of related complex proteins (glycoproteins) that transport Fe3+ iron ions in organisms. The carbohydrate component of transferrins constitutes approximately 5.5 percent. The molecular weight is approximately 80,000.

Transferrins occur in blood plasma, milk, and egg albumin (conalbumin). In blood plasma, their main functions are the transport of iron (with one molecule of transferrin binding two atoms of trivalent iron) to the reticulocytes, where hemoglobin is synthesized, and the maintenance of the Fe2+/Fe3+ ratio at a certain level. Upon electrophoresis of plasma proteins, transferrin is found in the β-globulin fraction. Transferrins are found in various genetically dependent forms, which have similar physical and chemical properties. A deficiency of transferrin in organisms leads to a number of pathological states caused by disruption of iron metabolism.


Glikoproteiny, vol. 2. Moscow, 1969. (Translated from English.)
The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
'The support granted under the SADC TRF comes at an opportune time when the country is reviewing its 2010 Trade Policy to embrace the economic changes which have taken place over the ten year period in both the two markets of SADC and EU,' she said.
As Rotarians sustain their giftgiving, the reach of TRF would be greatly enhanced if others, especially non-Rotarians do their share.
Now, TRF operates similar programs in nine different states, where approximately 10 to 15 inmate-students are enrolled at a time.
Second, some cases might be false positives because many of the reported symptoms are not specific to TRF exposure and might have been caused by unrelated factors or conditions.
To determine whether antioxidant properties alone are sufficient to ameliorate senescent myoblasts, in our study we tested a synthetic antioxidant, N-acetyl-cysteine (NAC), and its combination with TRF and ATF, besides treatment with TRF or ATF alone.
To determine the effect of vitamin E as an antioxidant, cell toxicity was induced by 12 hours incubation with 60 mM glutamate, followed by supplementation of 100, 200, or 300 ng/mL of either TRF or [alpha]-TCP for 24 hours in an atmosphere containing 5% C[O.sub.2] and 95% air.
The TRF weighted approach (Table 3) takes the same suppliers and attribute ratings but adds the weighted factor for each attribute.
The TRF fuel matrix (Table 1) is used to characterize the octane requirement of the engine when running at its optimal efficiency (optimal combustion phasing) [17],
The purpose of TBARS assay was to study the effects of TRF and [alpha]-TCP in quenching lipid peroxidation in the glutamate injured astrocytes.
-- The Food and Drug Administration's push for tamper-resistant formulations (TRFs) in the opioid market could result in the departure of non-tamper-resistant formulations, which currently dominate the sector, according to Frost & Sullivan.