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Any of various beta globulins in blood serum which bind and transport iron to the bone marrow and storage areas.



(also siderophilin), any of a group of related complex proteins (glycoproteins) that transport Fe3+ iron ions in organisms. The carbohydrate component of transferrins constitutes approximately 5.5 percent. The molecular weight is approximately 80,000.

Transferrins occur in blood plasma, milk, and egg albumin (conalbumin). In blood plasma, their main functions are the transport of iron (with one molecule of transferrin binding two atoms of trivalent iron) to the reticulocytes, where hemoglobin is synthesized, and the maintenance of the Fe2+/Fe3+ ratio at a certain level. Upon electrophoresis of plasma proteins, transferrin is found in the β-globulin fraction. Transferrins are found in various genetically dependent forms, which have similar physical and chemical properties. A deficiency of transferrin in organisms leads to a number of pathological states caused by disruption of iron metabolism.


Glikoproteiny, vol. 2. Moscow, 1969. (Translated from English.)
References in periodicals archive ?
5A presents several examples of TRF length of genomic DNA from colorectal tissues of either tumor (T) or non-tumor (NT) tissue.
For example, a monthly report of suppliers could be reviewed and any supplier with a TRF value over 25 would require documented investigation and possible corrective action.
The effects of TRF and [alpha]-TCP upon glutamate induced cytotoxicity were evaluated via MTT cell viability assay.
To indicate internal consistency of the TRF items, we calculated Cronbach's alpha for each TRF subscale, using data from the first child rated by each of the 19 teachers to avoid bias due to within-teacher correlation in the ratings of multiple children from the same teacher.
As expected, the TRF score has a significantly positive impact on offer size and underwriter reputation, and a significantly negative impact on underwriting spread, other offering-related expenses, and the SEO discount.
The TRF group watched the same videotaped lesson but applied an alternative framework.
There are some higher-molecular-weight bands in addition to the main telomeric smear present in both the coral and Symbiodinium TRF analyses; these could either represent higher-molecular-weight modes in the telomeres or simply be the result of incomplete digestion of DNA.
The TRF consists of 113 problem items, such as difficulty following directions, disturbing other pupils, and disrupting class discipline.
Tomorrow's TRF 525 final at Shelbourne will see Scolari Me Daddy opposed by the likes of Fatboyz Nodrog and Almost Chilli, while on Sunday the semis of the Munster Puppy Cup are at Clonmel.