Tetralin


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Tetralin

 

(or 1,2,3,4-tetrahydronaphthalene), a colorless liquid with an odor similar to that of naphthalene. Tetralin has a boiling point of 207.6°C and density of 0.970 g/cm3 at 20°C. It is insoluble in water but soluble in most organic solvents.

Tetralin is contained in the diesel fractions of petroleum and in coal oil. Produced industrially by the catalytic hydrogenation of naphthalene, it is used as an ingredient in degreasing substances, as a solvent in the paint and varnish industry, as a motor fuel additive, and as the raw material in the synthesis of certain dye intermediates.

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It has been shown that [5-HT.sub.1A] receptor agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) injected in anesthetized rats with DV model actiuated the voiding reflex, increased the frequency of bladder contractions, increased the voiding uolume, reduced bladder capacity, reduced intravesical pressure, and decreased PVR (10).
Various extremely simple hydrocarbons like n-butyl benzene, butadiene, styrene, acetylene and tetralin at a temperature of 700 [degrees]C forms some PAHs as a result of pyrolysis.
Hippocampal 8 [3H]hydroxy-2-(di-n-propylamino) tetralin binding site densities, serotonin receptor (5-HT1A) messenger ribonucleic acid abundance, and serotonin levels parallel the activity of the hypothalamopituitary-adrenal axis in rat.
The liquefaction reactions were carried out in a 500 ml batch autoclave with a motor driven stirrer (PARR Brand Model 4575, USA) in the presence of tetralin used as solvent under both noncatalytic and catalytic conditions in a nitrogen gas atmosphere (Fig.
The 5-HT6 receptors do not seem to be affected by MS, as the injection of its agonist, 8-hydroxy-2-(di-n-propylamin) tetralin (8-OH-DPAT), which has anxiolytic and antidepressant effects, does not manage to improve the anxious and depressive behaviors that separated adult animals display (Lambas-Senas et al., 2009).
Bazovkina, "Receptor-genes cross-talk: effect of chronic 5HT1A agonist 8-hidroxy-2-(DI-N-PROPYLAMINO) tetralin treatment on the expression of key genes in brain serotonin system and on behavior," Neuroscience, vol.
Decalin and tetralin," Industrial and Engineering Chemistry Research, vol.
Some of polycyclic aromatic hydrocarbons are formed through the pyrolysis of some very simple hydrocarbons like styrene, butadiene, n-butyl benzene, tetralin, and acetylene at a temperature of 700C.
Potential antidepressant properties of 8-hydroxy-2- (di-n-propylamino) tetralin, a selective serotonin 1A receptor agonist.
Jentys et al., "Bimetallic Pt-Pd/silica-alumina hydrotreating catalysts--part II: structure-activity correlations in the hydrogenation of tetralin in the presence of dibenzothiophene and quinolone," Journal of Catalysis, vol.