Thalassemia


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Related to Thalassemia: Thalassemia minor

thalassemia

[‚thal·ə′sē·mē·ə]
(medicine)
A hereditary form of hemolytic anemia resulting from a defective synthesis of hemoglobin: thalassemia major is the homozygous state accompanied by clinical illness, and thalassemia minor is the heterozygous state and may not have evident clinical manifestations. Also known as Mediterranean anemia.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Thalassemia

 

(also thalassanemia), a familial hemolytic anemia, first detected in 1925 among inhabitants of the Mediterranean region. Thalassemia is caused by disturbances in hemoglobin synthesis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
She appreciated Pakistan Bait-ul-Mal for establishing a national level state-of-the-art Pakistan Thalassemia Centre catering to the needs of millions of patients across Pakistan.
Ijaz Khan said due to thalassemia, not only the patients and their parents suffer the most, but they were also considered a burden on the society.
Zahir Ali Syed Director, UIT stated that - 'Our awareness activities focus on simple steps that can be implemented to reduce the condition's potentially devastating effects and improve the quality of life for thalassemia patients.
They believed that blood screening before marriages, counseling and awareness programs on thalassemia at all levels can reduce the risk of thalassemia among children.
Thalassemia is a blood disorder which passes down through families and results in an insufficient amount of hemoglobin in the blood, which is responsible for carrying oxygen.
A study conducted in Thailand showed that lack of maternal awareness related to antenatal screening is related to age, education, multi-gravidity and family history of thalassemia.11 A study conducted in Pakistan assessed that only 33% of the parents of thalassemic children had knowledge about premarital screening for detection of thalassemia trait and 76.5% had knowledge of prenatal screening.12 There is lack of scientific evidence on factors affecting parental knowledge about thalassemia major in Pakistan.
IGP Amir disclosed that when he served as the chief of the National Highways and Motorways Police (MHNP), he had visited the Shaukat Khanum Thalassemia Centre and other institutions and donated blood to set an inspiring example for officers under his charge.
The population of this study comprised of 1500 patients of beta thalassemia major registered at Fatimid Foundation, Peshawar.
The donation camp was arranged by Pakistan Bait-ul-Mal and donation drive drew a huge response from the students, faculty members and staff and especially girls who turned up to donate blood for children suffering from thalassemia and other patients.
Out of 2061 males, 91 (4.41%) were found to have beta thalassemia trait whereas among females only 6 (2.75%) out of 218 had beta thalassemia trait.
"Dr Yasmin Rashid is an active health minister and she is working diligently." Speaking on the occasion, Dr Yasmin Rashid said patients suffering from thalassemia are living as productive citizens of the society and the government's thalassemia prevention programme is working effectively in Punjab.
The pathogenic factors of thalassemia are hemolysis, ineffective erythropoiesis and the elevation in the absorption of iron, the defect in erythrocytes and precursor of erythroid that result from the first two factors are eliminated by phagocytosis of monocyte and macrophage which are subjected to hyperplasia and become hyperactive, and because of this hyper activity there will be defects in the phagocytosis of microorganisms (6).