Kellogg, "Quantification of theobromine
and caffeine in saliva, plasma and urine via liquid chromatography-tandem mass spectrometry: a single analytical protocol applicable to cocoa intervention studies," Journal of Chromatography B, vol.
She was given medication to reduce vomiting and stop her body absorbing theobromine
and caffeine are compounds found in chocolate, and many sugar-free or sugar substitute products contain xylitol.
Numerous studies have reported several significant bioactive groups in the cocoa and cocoa products including polyphenols (epicatechin, catechin and procyanidin) (Afoakwa et al., 2008; Arlorio et al., 2008; Ariza et al., 2014; Nsor-Atindana et al., 2012; Hii et al., 2009; Kim et al., 2014), methylxanthines (theobromine
, caffein and theophylline) (Caudle et al., 2001; Mhd-Jalil and Ismail, 2008), peptides (albumins, globulins, prolamin, and glutenin) (Voight et al., 1993; Mhd-Jalil and Ismail, 2008) lipids and sterols (Schwan and Wheals, 2004; Lim, 2012), fiber (Paoletti et al., 2012) as well as minerals (magnesium, copper and selenium).
and caffeine existing in tea are among the type of methylxanthines that are found in almost all types of teas.
Samples of caffeine, theophylline, theobromine
, spironolactone, propranolol, and ephedrine were supplied by Sigma (96 %).
The rich, highly concentrated cup of hot chocolate--almost with undetectable sugar content because of its high theobromine
and thickened by egg yolks--showed the character of a good Filipino chocolate.
Chocolate is poisonous because it contains the methylxanthine theobromine
, which is similar to caffeine and is used medicinally as a diuretic, heart stimulant, blood vessel dilator and a muscle relaxant.
About 300 people with a persistent cough are taking part in a clinical trial at 13 National Health Service hospitals in the UK where they are being given the naturally occurring chemical theobromine
, derived from the raw ingredient of chocolate, twice a day for 14 days.
COMPOUND dog food made in Spain under the brand names Megazookit and Vitcan Total Actividad has more concentrated amounts of theobromine
and caffeine than allowed in dog food.
Effect of cocoa and theobromine
consumption on serum HDL-cholesterol concentrations: a randomized controlled trial.