Thiazine Dye

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Thiazine Dye


any of a group of basic dyes whose molecules contain the thiazine heterocycle.

Among the thiazine dyes, methylene blue is of the greatest industrial significance.

Methylene blue is synthesized in three stages. First, a mixture of p-amino-N, N-dimethylaniline and sodium thiosulfate are oxidized by means of sodium bichromate, which forms sodium o-amino-m-dimethylaminobenzolthiosulfate. Second, N, N-dimethylaniline is added and, continuing the oxidation, “inda-mine-thiosulfonic acid” (Bindschädler’s Green) is produced. Finally, the reaction mass is heated together with bichromate and copper sulfate. During this stage a sulfite ion is detached and the thiazine ring is closed, forming methylene blue. This is a brilliant, intense dye, which is widely used for coloring paper and for the production of colored pencils and printing inks. (For the use of methylene blue in medicine, seeMETHYLENE BLUE.)

The blue, green, and black sulfur dyes are sometimes regarded as thiazine dyes.


Stepanov, B. I. Vvedenie v khimiiu i tekhnologiiu organicheskikh krasitelei [textbook]. Moscow, 1971.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Hachani, Decolorization kinetics of acid azo dye and basic thiazine dye in aqueous solution by UV/H2O2 and UV/Fenton: Effects of operational parameters, AUTEX Res.
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Methylene blue is a blue, organic cationic thiazine dye that has been commonly employed as a model dye to evaluate the photocatalytic activity among other photosensitizing dyes like eosin Y, pyrene, and so forth.
Background & objectives: Methylene blue (MB), a thiazine dye is used in the treatment of various methemoglobinaemias.
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Among their topics are enhancing the performance of polymeric materials through nanotechnology, edible nanocomposite films based on hydroxypropyl methyl cellulose reinforced with bacterial cellulose nanocrystals, synthesizing and characterizing silver nanoparticle sols in the presence of different polymeric stabilizers, the radiation protection properties of natural rubber composites, and a comparative study of metchromasy induced by thiazine dyes. Distributed by CRC Press, A Taylor & Francis Group member.
These include naturally occurring molecules such as chiorophylls, porphyrins, phthalocyanines, flavins, thiazine dyes, acridine dyes, anthraquinone dyes, xanthene dyes, hypercin, tetracyclines, sulfanilamides, psoralens, nalidixic acid, coal tar derivatives, chlorpromazines and aminobenzoic acid derivatives, to name but a few.
Nemcova, "Photophysical properties of thiazine dyes in aqueous solution and in micelles," Dyes and Pigments, vol.