Group Serum Testicular GSH testosterone (mmol/L) ([micro]g/g testis) Normal control 3.26 [+ or -] 0.14 57.63 [+ or -] 0.90 Thioacetamide
1.71 [+ or -] 0.11 38.59 [+ or -] 1.55 TAA+Candesartan 2.82 [+ or -] 0.18 (*) 55.31 [+ or -] 1.33 (*) TAA+Losartan 2.90 [+ or -] 0.14 (*) 53.75 [+ or -] 1.09 (*) Group Testicular MDA (mmol/mg protein) Normal control 16.91 [+ or -] 0.45 Thioacetamide
29.61 [+ or -] 0.63 TAA+Candesartan 17.65 [+ or -] 0.32 (*) TAA+Losartan 18.14 [+ or -] 0.38 (*) Data was expressed as mean [+ or -] SEM.
Nardostachys jatamansi protects against liver damage induced by thioacetamide
Lunova et al., "Standard operating procedures in experimental liver research: thioacetamide
model in mice and rats," Laboratory Animals, vol.
(5 [cm.sup.3] of 1.33 M) was then added to the mixture.
Effects of losartan and candesartan on the levels of: A, serum tumor necrosis factor-[alpha] (TNF-[alpha]), B, hepatic malondialdehyde (MDA), C, hepatic glutathione (GSH), and D, hepatic expression of TNF-[alpha] mRNA in thioacetamide
(TAA)-induced chronic liver failure rats.
Protective effects of Phyllanthus acidus (L.) Skeels leaf extracts on acetaminophen and thioacetamide
induced hepatic injuries in Wistar rats.
Rg1 has been found as an antioxidant substance and attenuated the oxidative damage in liver of thioacetamide
treated rats (Deng and Zhang 1991; Geng et al.
Furthermore, animal studies showed that NLRP[3.sup.-/-] and AS[C.sup.-/-] mice were resistant to liver fibrosis induced by carbon tetrachloride or thioacetamide
, with reduced expression of TGF-[beta] and collagen-1 .
The objective was to evaluate the role of ethanolic extract of Moringa oleifera leaf (MOE) administered orally followed by low doses of gamma-irradiation (LDR) on thioacetamide
(TAA) induced liver fibrosis in female albino rats.
A number of thioacetamide
and sulfonyl acetamide derivatives of glycosyl were found to possess antitubercular activity .