The DZN exposure significantly decreased (P<0.001) the total thiol groups
in the liver and kidney, when compared to those in the control group.
However, thiol groups
are susceptible to oxygen-converting thiols into disulfides via oxidative coupling .
Kehoe, The Thiol-Activated Toxin Streptolysin O Does Not Require a Thiol Group
for Cytolytic Activity, Infect.
Also, there was a positive correlation between lipid peroxidation of labor and thiol groups
and total antioxidant capacity in women with their newborns3,7.
In a similar study, it was shown that captopril, an ACE inhibitor with a thiol group
, does not affect OVA-induced IgG responses in mice immunized with this antigen in complete Freund's adjuvant (12).
This volume presents information on the synthetically useful protective groups in chemical reactions, focusing on major functional groups: the hydroxyl group, phenols and catechols, the carbonyl group, the carboxyl group, the thiol group
, the amino group, the alkyne-CH, and the phosphate group.
Thiomers exhibit improved mucoadhesive properties due to formation of covalent bond between thiol group
of polymer and cysteine rich subdomains of mucus glycoprotein.
In other ways, the potential coordinating sites are sulphur atom of the thiol group
, nitrogen atoms of the amino group, and oxygen atoms of the carboxyl group and hydroxyl group.
The method is comprised of attaching a reactive group X--Y to a surface of a pigment; and subsequently displacing Y with an organic substrate N--S--ZM to form a surface-modified pigment having attached X--N--S--ZM; wherein X is a sulfonyl, phosphoryl, or 1,3,5-triazine group; Y is fluorine, chlorine, bromine or iodine; N is an amine, an imine, a pyridine, or a thiol group
; S is substituted or unsubstituted alkyls, aryls, or polymer chains having a molecular weight range from approximately 300-8000; Z is a carboxyl, sulfonyl, phenolic, phosphoryl, ammonium, trimethylammonium, or tri-butylammonium group; and M is a halide, a negatively charged ion, a proton n salt form, or a cation in salt form.
In thiocholine, the thiol group
(a sulfur atom) is at an end of the molecule and is reactive.
In situ gelation of thiolated chitosan could be resulted from Michael addition in a mild condition between the grafted thiol group
in chitosan and double bonds in poly(ethylene glycol) diacrylate (PEGDA) (14), (15).