Thymidine


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thymidine

[′thī·mə‚dēn]
(biochemistry)
C10H14N2O5 A nucleoside derived from deoxyribonucleic acid; essential growth factor for certain microorganisms in mediums lacking vitamin B12 and folic acid.

Thymidine

 

a natural organic compound, a nucleoside consisting of the pyrimidine base thymine and the carbohydrate deoxyri-bose. Thymidine is made up of acicular crystals that are readily soluble in water. With respect to chemical properties, it is a weak base. Thymidine is present in all living cells as a constituent of deoxyribonucleic acid (DNA). Thymidine tagged with radioactive tritium is extensively used in laboratories to study DNA biosynthesis and the repair of DNA after injury.

References in periodicals archive ?
Thymidine Market Segment by Regions, splits into several key Region, with production, consumption, revenue, market share and growth rate of Thymidine Market in these regions, from 2011 to 2021 (forecast), like North America, China, Europe, Japan, India, Southeast Asia split by product type, with production, revenue, price, market share and growth rate of each type Split by application, this report focuses on consumption, market share and growth rate of Thymidine Market in each application.
Regulation and biological function of thymidine kinase.
Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir.
Phase II study of Capecitabine with concomitant radiotherapy for patients with locallyadvanced pancreatic cancer: up-regulation of thymidine phosphorylase.
10 [micro],Ci (250 nM) 3H-labeled thymidine was subsequently added for the duration stated.
A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy.
We know that viral replication can occur in the absence of viral thymidine kinase, in addition, there do exist HSV strains that have dysfunctional thymidine kinase that are immune to oral nucleoside analogues," said Dr.
Literature studies on thymidine complexes is scarce due to the lack of both precise structural and solution chemical data.
Thymidine analogue use was considered to be the leading risk factor for lipoatrophy development.
NRTI cross-resistance and the accumulation of thymidine analogue mutations (TAMs) were both associated with length of time on antiretroviral treatment and zidovudine (AZT) use; tenofovir (TDF) use was additionally linked to NRTI cross-resistance.
Thymidine phosphorylase: Tumors that express thymidine phosphorylase (TP) are more aggressive but also more responsive to treatments such as radiation, anthracyclines, and taxanes.

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