thymocyte

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Related to Thymocytes: thymus

thymocyte

[′thī·mə‚sīt]
(histology)
A lymphocyte formed in the thymus.
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Calcium-dependent killing of immature thymocytes by stimulation via CD37T cell receptor complex.
Thymic nurse cells participate in heterotypic internalization and repertoire selection of immature thymocytes; their removal from the thymus of autoimmune animals may be important to disease etiology.
Decreased signaling competence as a result of receptor overexpression: over-expression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes. Proc Natl Acad Sci USA 1993;90:10534-8.
However, after puberty and with advanced age, the thymic space becomes progressively filled with adipocytes and there is a dramatic loss of thymocytes in the cortical and medullary areas, leading to a reduction in the synthesis of T cells.
The mitochondrial and death receptor pathways involved in the thymocytes apoptosis induced by aflatoxin B1.
The lymphopoiesis in thymus is complex and requires intricate interactions of thymocytes with specialized thymic microenvironment2.
In 1972, Zeiller and Dolan12 showed in experiments in mice and rats that thymocytes are not derived from the thymus but rather originate from the bone marrow and migrate to the thymus.
The percentages of the positive samples in thymocytes were determined.
However, in the thymus, SPL is strongly expressed in thymic stromal cells, whereas its expression in thymocytes is barely detectible.
cruzi has been also associated with modulation of different aspects of the antiparasitic immune response, by inhibiting plasma cell differentiation and production of immunoglobulins [22] and promoting the release of immature thymocytes [23].
Garlic (Allium sativum) lectins ASA I and ASA II revealed a mitogenic effect in human peripheral blood lymphocytes, murine splenocytes, and thymocytes and stimulated in vitro histamine release from leukocytes in atopic patients when compared with nonatopic individuals [85].
Fairbairn et al., "Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress," Nature Communications, vol.