Titer


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titer

[′tī·tər]
(chemistry)
The concentration in a solution of a dissolved substance as shown by titration.
The least amount or volume needed to give a desired result in titration.
The solidification point of hydrolyzed fatty acids.
(textiles)
The weight per unit length of yarn.
The number of filaments in reeled silk thread.

Titer

 

(in analytical chemistry), the concentration of a solution expressed as the amount (in grams) of a substance dissolved in 1 milliliter (ml) of solution or as the amount of any substance that reacts with 1 ml of the given solution. Accordingly, a distinction is made between the titer for a dissolved substance (for example, the titer of the solution of hydrochloric acid, THCI) and the titer for a substance to be determined (for example, the titer of the solution of hydrochloric acid for sodium hydroxide, THCI/NaOH). The titer is calculated from the formula T = P/V, where T is the titer of the solution in g/ml, P is the weight of the batch in g, and V is the volume of the measuring flask in ml. Solutions with a known titer, called standard solutions, are used in titrimetric analysis.


Titer

 

in immunochemical analysis, the maximum or optimum dilution of antigens, antibodies, or complement at which a positive reaction between antigens and antibodies can be recorded or the reaction of one or both components can be registered against a standard. In some cases, such as complement fixation, the maximum antigen concentration at which sensitized erythrocytes can still be lysed is taken as the antigen titer. Determination of the titer is useful in making a quick estimate of the activity of immune serums.

Three kinds of titration are used in immunochemical analysis. In one method, pipettes are used to add different amounts of the material being titrated to identical volumes of the solvent or for successive transfer of a mixture of the material and solvent to test tubes containing an identical quantity of solvent; in the latter case, equal volumes of the material, solvent, and mixture to be transferred are usually taken, which produces twofold dilutions. The second method is similar, except that capillary tubes are used and the volumes are measured from the number of drops. Glass loops capable of holding strictly standard volumes of liquid are used in automatic titration.

N. A. DORFMAN


Titer

 

(titre), in the textile industry, a number used to rate the thickness of fibers and yarns (chiefly silk). The titer is expressed as the product of the cross-sectional area of a fiber or yarn and the density of its material (or as the ratio of the weight of a fiber or yarn to the length). The titer came into use in the 18th century. A unit known as a legal titer has been used since 1900; it is numerically equivalent to the weight in grams of a yarn 9 km in length. In the USSR the tex replaced the titer in 1956.

References in periodicals archive ?
Considerable rate of failure in maintaining acceptable titer levels following routine vaccination against HBV was found.
Serum samples from three chicks showed HI titer of 1: 32, ten chicks indicated HI titer of 1: 16 and seven chicks had HI titer of 1: 8.
There is an ongoing debate among clinicians about the real utility of ASO titer levels.
On day 150, 210, 240, 270, and 300 the mean RVNA titer of group C was significantly higher than those of groups A and B.
Similar concentration-dependent titer reduction by addition of exogenous recombinant human tTG suggests that sequestration of anti-tTG antibodies by endogenous RBC-tTG is the mechanism responsible.
Crouch of the State University of New York at Stony Brook and her colleagues recommend that antibody titers should be tested before revaccinating adopted children who have documentation of vaccines that were given in their countries of origin.
05) vaccination responses but, contrary to expectations, there was a tendency to higher antibody titers with increasing levels of AF-alb.
Tony Milici, CEO of GeneThera remarked, "GeneThera's PURIVAX(TM) is able to achieve both high purity and high viral titer (up to 10e16 viral particles/eulate) based on its proprietary multi-resin anion exchange chromatography system, unlike traditional technologies and first generation chromatography processes that are inadequate, both in terms of purity and yield.
We compared antibody titers of laboratory workers who worked with a CAP sample with those who did not.
The patient's fluorescent treponemal antibody titer and antistriatal antibody titer were normal, as was her erythrocyte sedimentation rate (ESR).