topical

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topical

(of a drug, ointment, etc.) for application to the body surface; local
References in periodicals archive ?
(3.) Topical Drug Delivery Market Growing at a CAGR of 6.4% During 2017 to 2021.
Emulsion and gel could be mixed in preparation called emulgel,5 O/W emulsion for lipophilic materials while W/O for hydrophilic materials.6 Emulgels are thixotropic, greaseless, easily spreadable, easily removable, emollient, non-staining, bio-friendly, transparent and cosmetically acceptable.2 They also have good cutaneous penetration7 and long shelf-life.8 This all make emulgels an advantageous topical drug delivery system.
Nonetheless, they write formulating topical drugs as liquid salts shows promise for improving delivery.
Lipospheres are lipid-based encapsulation system, used for topical drug delivery of various medicaments.
The development of nanosystems for topical drug delivery to target cells is a promising tool.
AKs are commonly treated with cryotherapy (freezing) and, more recently, with photodynamic therapy--which uses laser light and a photosensitizing topical drug to kill cancer cells--or topical medications such as fluorouracil or imiquimod, which require weeks to months of use and can cause skin irritation during this time.
The company operates 200,000 square feet of state-of-the-art manufacturing facilities and offers topical drug product expertise and turn-key project management including formula development, package sourcing and testing, method development and validation, IC11 stability programs, bulk manufacturing, filling and regulatory filing assistance.
"While transdermal and other topical drug therapies are more popular in Europe and Asia, the United States is still predominately a pill-popping culture," says John Incledon, President and Chief executive Officer of Hisamitsu America, Inc.
Based upon the peak sales of the topical product Penlac ($125 million US, 5.5%-8.5% efficacy) and Lamisil ($1.2 billion world-wide, 38% efficacy, but with the risk of liver failure and death), we believe a topical drug that is both safe and effective can generate peak sales of $700 million by 2020 in the U.S."
is a privately held company that specializes in the development of topical drug products for pharmaceutical and biotechnology clients.
The FDA has announced that companies marketing unaproved ophthalmic balanced salt Solutions (BSS) and unapproved topical drug products containing papain must stop manufacturing and marketing these products or risk enforcement action.
Studies have shown that the topical drug penetrates the skin and is seen at high levels in the subcutaneous tissues and synovium, with the concentration and persistence in the synovium being similar to orally administered diclofenac.