A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration
compared with mediastinoscopy for mediastinal lymph node staging of lung cancer.
Blind transbronchial needle aspiration
without an onsite cytopathologist.
Arenberg, "Endobronchial ultrasound-guided transbronchial needle aspiration
for non-small cell lung cancer staging," American Journal of Respiratory and Critical Care Medicine, vol.
Endobronchial ultrasound guided transbronchial needle aspiration
of mediastinal lymph nodes for lung cancer staging: a projected cost analysis.
Cytology Specimen Types and Collection Techniques Based on Location of the Lesion Specimen Type and Collection Technique Site of Lesion Sputum, BW, BB Proximal mucosal lesion TBNA or transtracheal Proximal submucosal lesion FNA with (EBUS) or Peribronchial, tracheal, without guidance carinal lesion Mediastinal lesion TTNA, BB, BAL Peripherally located parenchymal lesion Abbreviations: BAL, bronchoalveolar lavage; BB, bronchial brushing; BW, bronchial washing; EBUS, endobronchial ultrasound; FNA, fine-needle aspiration; TBNA, transbronchial needle aspiration
; TTNA, transthoracic needle aspiration.
A rare constellation of empyema, lung abscess, and mediastinal abscess as a complication of endobronchial ultrasound-guided transbronchial needle aspiration
. Eur J Cardiothorac Surg 2011;40:264-5.
Siegelman, "Flexible transbronchial needle aspiration
for staging of bronchogenic carcinoma," Chest, vol.
Ayub et al., "Initial experience with endobronchial ultrasound-guided transbronchial needle aspiration
(EBUS-TBNA) from a tuberculosis endemic population," Journal of Bronchology & Interventional Pulmonology, vol.
The investigation of suspected cases of intrathoracic TB, is greatly aided by means of aspiration of the intrathoracic lymph nodes and tracheobronchial wall-adjacent lung lesions by using endobronchial ultrasound-guided transbronchial needle aspiration
. In a study by Sun et al (2013)28 the sensitivity, specificity, positive and negative predictive values were 85%, 100%, 100% and 75%, respectively.
Similarly, the diagnostic yield of FB for mediastinal lymph nodes using transbronchial needle aspiration
(TBNA) is reported to be between 15-83% .
Graph 1: The diagnostic sensitivity of endobronchial ultrasound-guided transbronchial needle aspiration
in consecutive clusters (P = 0.054) Patients # 1-20 92,9 21-40 100 41-60 94,3 61-80 100 81-100 98,4 Note: Table made from bar graph.
In this review, we will discuss a new field for molecular lung cytopathology focusing on the analysis of molecular drivers of resistance using NGS technology on cytology specimens from the endobronchial ultrasound-guided transbronchial needle aspiration
(EBUS-TBNA) of NSCLC patients with thoracic progression after/on TKI therapy.