recognized this transfusion reaction as a distinct clinical entity and coined the term transfusion-related acute lung injury
The effect of previous pregnancy and transfusion on HLA alloimmunization in blood donors: implications for a transfusion-related acute lung injury
risk reduction strategy.
11] Transfusion also increases the risk of allo-immunization, hemolytic and allergic reactions and transfusion-related acute lung injury
identify common issues and errors associated with the blood transfusion process, to help general practitioners, trainees, individuals working in the clinical laboratory, laboratory managers, and hospital administrators learn about common types of errors they are likely to encounter, and address issues such as making decisions about when to premedicate patients, strategies of warfarin reversal, and the diagnostic intricacies of thrombocytopenic pupura and transfusion-related acute lung injury
These include allergic reactions, transfusion-related acute lung injury
(TRALI), haemolysis, fluid overload and infectious complications.
Blood-borne infections, non-infectious complications including allergic, anaphylactic and haemolytic transfusion reactions, transfusion-related acute lung injury
and transfusion-associated circulatory overload are common and lead to significant morbidity and mortality (15).
Above all, considering the confusing diagnostic possibilities, including opportunistic infections, congestive heart failure, and transfusion-related acute lung injury
, and several toxic agents, exact diagnosis of hyper-sensitivity pneumonitis should rely primarily on characteristic HRCT features and lymphocytosis in bronchoalveolar lavage, so as to minimize the likelihood of misdiagnosis.
Only the plasma from male donors can be used - giving seriously ill patients plasma from female donors can result in them developing transfusion-related acute lung injury