Encephalopathy

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Related to Transmissible spongiform encephalopathy: bovine spongiform encephalopathy

encephalopathy

[en‚sef·ə′läp·ə·thē]
(medicine)
Any disease of the brain.

Encephalopathy

 

a collective term that designates a noninflammatory organic disease of the brain. Some encephalopathies are innate, resulting from embryopathy. Others are the result of infection, poisoning, trauma, or vascular disease of the brain. There are no specific manifestations. The most common encephalopathies resemble neuroses (asthenia, irritability, insomnia, headaches) or psychoses (narrowed scope of interests, passivity, emotional instability, vulgarity). Symptoms may include memory loss or mental deterioration.

Alcoholic encephalopathies are alcoholic psychoses. They may be acute, as in Wernicke’s encephalopathy (named for the German neuropathologist C. Wernicke, who described the condition in 1881), or chronic, as in Korsakov’s psychosis (named for S. S. Korsakov) and alcoholic pseudoparalysis. Lead encephalopathy is caused by chronic poisoning by lead salts.

Treatment for encephalopathies depends on the cause of the disease.

References in periodicals archive ?
The distribution of infectivity in blood components and plasma derivatives in experimental models of transmissible spongiform encephalopathy.
Differences in molecular mass observed between protease-resistant prion protein in cattle bovine spongiform encephalopathy (BSE) and usual transmissible spongiform encephalopathy cases in small ruminants.
Experimental transmission of Stetsonville TME into cattle resulted in transmissible spongiform encephalopathy (TSE) disease with an incubation period of 18.
Cattle sources of transmissible spongiform encephalopathy (TSE) used for experimental infections of C57BL/6 mice an transmission results * Cattle TSE isolate Age, y Breed Molecular type 1 8 Charolais H 2 12 Crossbreed H 3 4 Prim'Holstein Typical Survival periods (d) Cattle TSE in C57BL/6 mice Western blot isolate (mean [+ or -] SD) results ([dagger]) 1 702 [+ or -] 117 8/9 2 652 [+ or -] 85 10/10 3 511 [+ or -] 89 8/9 * SD, standard deviation.
The risk is only present when a killed animal, although healthy, is incubating a Transmissible Spongiform Encephalopathy (TSE) such as BSE and there is an infection in the brain.
A report on "The evaluation of tests for the diagnoses of transmissible spongiform encephalopathy in bovines" will be published by the European Commission in a leading scientific journal as soon as possible.
Guidelines for transmissible spongiform encephalopathy testing should be followed.
On July 22, the EU executive issued a Recommendation to the Member States, as well as to third countries, on providing information required to assess their transmissible spongiform encephalopathy (TSE) status.
b) The initial case of transmissible spongiform encephalopathy in a cheetah occurred in Australia, one case in the Republic of Ireland, and three cases in France; all animals were born in Britain except the most recently reported case in France.
Defects in either the complement pathway or follicular dendritic cells result in resistance to peripheral scrapie infection (7,8), and this resistance likely occurs for peripheral transmissible spongiform encephalopathy infections in general.

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