When the researchers gave mice that were injected with human lung cancer cells trifluoperazine in combination with the targeted lung cancer drug erlotnib, the tumors shrank much more than in mice treated with either drug by itself.
Both drugs are already approved by the US Food and Drug Administration - erlotinib is sold under the brand name Tarceva and trifluoperazine is marketed under the brand name Stelazine.
Of note is that all the subjects currently on the antipsychotic trifluoperazine
, and those on fluphenazine depot, were found to be at low suicide risk and had low BHS and CDSS scores.
Her only medical history consisted of bipolar disorder, which was treated with 400 mg lithium and 1 mg trifluoperazine
Therefore in our dinic, it is our standard approach to continue treatment in patients who are dependent on a typical high-potency antipsychotic, such as haloperidol, fluphenazine hydrochloride (Prolixin, Permitil), or trifluoperazine
(Stelazine), or a midpotency antipsychotic.
At the time of his suicide he was being treated with trifluoperazine
and depot fluphenazine, after flupentixol and zuclopenthixol had been tried previously.
Beecher said, adding that he also occasionally uses older antipsychotics as mood stabilizers, including trifluoperazine
Only three patients in his clinic developed DIP in response to typical antipsychotics (haloperidol, trifluoperazine
, and amoxapine).
Today, he takes the antianxiety/antipsychotic trifluoperazine
hydrochloride (Stelazine) as needed.
In a blind and placebo-controlled pilot study, five female patients had been diagnosed with schizophrenia and were receiving haloperidol (Haldol), trifluoperazine
, fluphenazine, or risperidone (Risperdal) (J.