Trifluoperazine


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Related to Trifluoperazine: Trifluoperazine hydrochloride

Trifluoperazine

 

(or triftazin), one of the psychotropic drugs. Trifluoperazine has a more active antipsychotic effect than chlorpromazine. It also has a marked antiemetic effect. It is used internally and intramuscularly in the treatment of schizophrenia and manic-depressive psychosis.

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Seubert, Separation of Metal- Trifluoperazine Hydrochloride Complexes Using Zwitterionic Ion Chromatography (ZIC) Coupled Online with ICP-AES, Curr.
Sexual dysfunction in male subjects receiving trifluoperazine, risperidone, or olanzapine: rates vary with assessment questionnaire.
Trifluoperazine (TFP) is a CaM antagonist that has been used to explore Ca2+-CaM dependent activation of various enzymes.
Table 2: Total score of individual FDC FDC Total score Amitryptaline + chlordiazepoxide 9 Escitalopram + clonazepam 8 Etizolam + propranolol 9 Chlorpromazine + trihexyphenidyl 8 Olanzapine + fluoxetine 14 Clonazepam + propranolol 7 Risperidone + trihexyphenidyl 7 Escitalopram + etizolam 6 Propranolol + flunarizine 5 Paroxetine + clonazepam 12 Trifluoperazine + trihexyphenidyl 7 Donepezil + memantine 12 Desvenlafaxine + clonazepam 6 Pregabalin + methylcobalamin 13 FDC, fixed-dose combination.
Prescribed typical antipsychotics within the study period included chlorpromazine, clopenthixol, clothiapine, droperidol, flupentixol, fluphenazine, haloperidol, levomepromazine, loxapine, methotrimeprazine, perphenazine, pipotiazine, sulpiride, thioridazine, thiothixene, and trifluoperazine.
Discontinue if jaundice develops Trifluoperazine Phenothiazines are contraindicated with significant hepatic impairment Source: Dosage modification suggestions adapted from Clinical Pharmacology.
Trifluoperazine is approved for GAD, as a short-term treatment.
The drugs whose utilization accounted for about 90% of the entire drug use (DU 90%) include haloperidol, amitriptyline, benzhexol, trifluoperazine, chlorpromazine, and carbamazepine.
94) Also, another study (95) suggests that an existing phenothiazine-like antipsychotic drug, trifluoperazine, has the ability to down-regulate cancer stem cell markers CD44 and CD133 and as such might possess anti-lung cancer stem cell properties.
5-10 mg Medium Potency Trifluoperazine Stelazine 1-10 mg Typical Perphenazine Trilafon 2-16 mg Thiothixene Navane 2-20 mg Loxapine Loxitane 5-50 mg Low Potency Molindone Moban 5-100 mg Typical Mesoridazine Serentil 10-100 mg Thioridazine Mellaril 10-200 mg Chlorpromazine Thorazine 10-200 mg Adapted from Wilens (1999) and Li, Pearrow, & Jimerson (2010).
Researchers from Case Western Reserve University School of Medicine and Mount Sinai School of Medicine found that the anti-psychotic medication trifluoperazine can reactivate a gene pathway involved in tumor suppression that's normally turned off in lung cancer patients.
8 mM ketamine and 1[micro]M MK801, 15 min (treatment 1), 100 [micro]M nifedipine and 100 [micro]M flavoxate hydrochloride, 30 min (treatment 2) and 10 [micro]M trifluoperazine, 30 min (treatment 3).