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Related to Trypanosoma brucei: Trypanosoma cruzi
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a genus of protozoans of the class Flagellata that parasitize the blood and tissues of vertebrates, including man. There are several dozen species, many of which are pathogenic. The body is spindle-shaped and has a single nucleus. The flagellum originates in the cytoplasm of the posterior third of the body from the basal corpuscle. It protrudes freely and forms an undulating membrane with the fold of the pellicle. Alongside it is a kinetoplast, a mitochondrion-like organelle that abounds in DNA. Members of the genus reproduce by longitudinal division. There is no sexual process. Most species penetrate into the body of a vertebrate animal or man through transmitters, usually in-sects. The insects either transmit the parasites mechanically with their piercing mouth parts or serve as temporary hosts to the parasites, which reproduce and undergo a succession of morphological changes, becoming crithidiae and leptomonae.

T. gambiense and T. rhodesiense are pathogenic for man; they cause African sleeping sickness, transmitted by flies of the genus Glossina. T. evansi (the causative agent of surra) and T. brucei (the causative agent of nagana) parasitize cattle in Africa and India. In the USSR, camels suffer from su-auru, caused by T. ninaekohlyakimovi, and horses and donkeys suffer from dourine, caused by T. equiperdum.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Rademacher, "The glycosylphosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoprotein," Biochemical Society Transactions, vol.
The parasites tested were Trypanosoma brucei rhodesiense STIB 900 strain, Trypanosoma cruzi Tulahuen strain C2C4 containing the [beta]-galactosidase (Lac Z) gene and Leishmania donovani strain MHOMJET/67/L82.
The origins of a new Trypanosoma brucei rhodesiense sleeping sickness outbreak in eastern Uganda.
Bidirectional activating signals between Trypanosoma brucei and CD8+ Tcells: a trypanosome-released factor triggers interferon-gamma production that stimulates parasite growth.
Human African Trypanosomiasis (HAT) also known as sleeping sickness is caused by Trypanosoma brucei rhodesiense (in East and South Africa) or Trypanosoma brucei gambiense (in West and Central Africa) (1).
Keywords: Essential oil Hagenia abyssinica Leonotis ocymifolia Moringa stenopetala Trypanosoma brucei brucei HL-60
Immunization of mice against Trypanosoma brucei infections by administration of released antigens absorbed to erythrocytes.
Sleeping sickness is caused by the bite of a tsetse fly carrying the protozoan Trypanosoma brucei. Earlier work showed that a compound called Z-Phe-Ala-CH[N.sub.2] could kill the microbe in a lab dish.
[3] quienes indicaron que la infeccion con Trypanosoma brucei brucei en diferentes estadios de la gestacion, resulto en un 16% de abortos, 100% de mortalidad y 33,3% de neonatos no viables.
Human African trypanosomiasis (HAT), known as African sleeping sickness, is a protozoal infection, the West African form of which is caused by Trypanosoma brucei gambiense.