tubulin

(redirected from Tubulins)
Also found in: Dictionary, Medical.
Related to Tubulins: alpha tubulin

tubulin

[′tü·byə·lən]
(biochemistry)
A globular protein containing two subunits; 10-14 molecules are arranged to form a microtubule.
References in periodicals archive ?
Its wall is made up of 13 protofilaments, each consisting of heterodimeric subunits containing two related tubulin proteins.
Some well-known housekeeping genes, such as actin, tubulin, ribosomal RNA, and elongation factor 1 alpha, are necessary for cell survival, and highly abundant proteins in all cell types.
These lines of studies, as well as analyses by X-ray diffraction and nuclear magnetic resonance, are expected to join single molecular imaging technique and reveal structure-function relationship in dyneins and between dynein and tubulin. Ultimately it might become possible to answer the questions why dyneins are so big, why tubulins undergo a variety of post-translational modifications and why multiple dynein heavy chains are needed for flagellar and ciliary motility.
Craddock et al calculate enormous information capacity at low energy cost, demonstrate microtubule-associated protein logic gates, and show how patterns of phosphorylated tubulins in microtubules can control neuronal functions by triggering axonal firings, regulating synapses, and traversing scale.
Protist tubulins: new arrivals, evolutionary relationships and insights into cytoskeletal function.
(Rockville, MD) announced that it has entered into an exclusive worldwide license agreement with Celgene Corporation (Summit, NJ) for the development and commercialization of Celgene's small molecule tubulin inhibitor compounds for the treatment of cancer.
Staley of the University of Washington in Seattle now report that the bacterium Prosthecobacter dejongeii has two genes that are "incredibly similar" to the eukaryotic genes for tubulin's subunits.
Using a cell line in which tubulin was labeled with the fluorescent indicator green fluorescent protein (GFP) and immunofluorescence assay, G.W.
This distinction was not possible because of the limitations of gamma tubulin staining.
The polymorphic sites were identified by using the standard set of ambiguity nucleotides through CLC Genomics work bench (CLC bio) and BLAST searches at NCBI/primers used to generate the AY- tubulin gene sequence from H.
The objective of this study was to isolate and characterize the b- tubulin gene from B.
The main constituents of the cytoskeleton consist of microtubules which are like hollow cylinders of 25 nm in diameter, of variable length (from micrometers to milimeters, depending on whether they are contained within dendrites or axons) and are composed of assemblies of [alpha]/[beta] tubulin dimers.

Full browser ?