The second variable corresponds to HPLC quantification of biogenic amines (histamine,
tyramine, putrescine, cadaverine and phenylethylamine)
Tyramine is one kind of monoamine, also known as 2-(4-hydroxyphenyl) ethylamine which occurs naturally in cheese and other foods.
Monoamine oxidase inhibitors: a review concerning dietary
tyramine and drug interactions.
The eight studied amines were putrescine (PUT), cadaverine (CAD), histamine (HIM),
tyramine (TYM), serotonin (SRT), agmatine (AGM), spermidine (SPD) and phenylethylamine (PEM).
Tyramine and 2-phenylethylamine were only found in group B2 with very low amount of 0.3 [micro]g/g.
Tyramine and guaiacol are metabolic products of tyrosine, which is closely related to the synthesis of catecholamine.
In vitro, transduction of cardiomyocytes with a MAO-A adenovirus in the presence of
tyramine reproduced mitochondrial damage, diminished ATP production, and decreased PGC-1a expression and necrosis through ROS generation.
Names: doxycycline, tetracycline (MAOIs) Antidepressants- Foods that contain high Monoamine Oxidase Inhibitors: amounts of
tyramine can spike Treat depression by balancing blood pressure.
Amine compounds were identified and quantified based on comparison with standard curves constructed from pure compounds (histamine, methylamine, ethylamine and
tyramine).
The most common biogenic amines found in foods are histamine,
tyramine, cadaverine, 2-phenylethylamine, spermine, sperm idi ne, putrescine, tryptamine, and agmatine.
Although no information in Brazilian legislation on the safe levels of bioactive amines ingestion is available, it is already known that the consumption of great amounts of histamine,
tyramine and phenylethylamine may have toxic effects on humans.
Formation of histamine and
tyramine by some lactic acid bacteria in MRS broth and modified decarboxylation agar.
