kinase

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Related to Tyrosine kinase: Tyrosine Kinase Receptor

kinase

[′kī‚nās]
(biochemistry)
Any enzyme that catalyzes phosphorylation reactions.
References in periodicals archive ?
2 XLA is caused by mutations in the Bruton tyrosine kinase (Bkt) gene.
Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development.
These data suggest a way in which receptor tyrosine kinase inhibitors could be used to treat individuals with KRAS mutant colorectal cancers.
The tyrosine kinases are often dysregulated in malignancy.
Inhibition of EGFR may be achieved by a variety of mechanisms including utilising antisense or small interference RNA to suppress EGFR gene expression [14], the use of tyrosine kinase inhibitors that target the intracellular tyrosine kinase domain, or the use of monoclonal antibodies that target the extracellular domain and inhibit ligand binding.
We believe that soluble endoglin [a cell surface receptor for the proangiogenic protein transforming growth factor-[beta] and soluble fms-like tyrosine kinase 1 [an antiangiogenic factor that binds placental growth factor and vascular endothelial growth factor] act in concert to produce the maternal syndrome or preeclampsia," he said.
Specifically, Tarceva inhibits tyrosine kinase activity, which is associated with EGFR.
Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors.
Exposure to R5 gp120 and X4 gp 120 resulted in activation of pro line-rich tyrosine kinase 2 (Pyk2), a non-receptor tyrosine kinase related to focal adhesion kinase.
These findings provide strong evidence that the failure of normal B-cell growth and differentiation in XLA is caused by abnormal function of an intracellular protein tyrosine kinase.
Soybeans, like most legumes, are rich in isoflavones, which inhibit the activity of tyrosine kinase.

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