UBA2 | Article about UBA2 by The Free Dictionary
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The fortress or citadel of an ancient town.
McGraw-Hill Dictionary of Architecture and Construction. Copyright © 2003 by McGraw-Hill Companies, Inc.
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Therefore, whether SUMO can modify HIPK2 is affected by ROS levels since high levels of it can block sumoylation probably due to the reversible formation of disulfide bonds between catalytic cysteines of the SUMO E1 subunit Uba2
and the E2-conjugating enzyme Ubc9  or by ROS-mediated stabilization of SENP .