Uronic Acid

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Related to Uronic acids: aldonic acids

uronic acid

[yə′rän·ik ′as·əd]
(organic chemistry)
One of the compounds that are similar to sugars, except that the terminal carbon has been oxidized from the alcohol to a carboxyl group; for example, galacturonic acid and glucuronic acid.

Uronic Acid


any of the organic substances that are related to monosaccharides but that are distinguished from the latter by having a carboxyl group (—COOH) in place of the—CH2OH radical. The difference is illustrated by the following structural formulas:

Uronic acids are crystalline or amorphous substances that are nonvolatile, relatively high-melting, and readily soluble in water and polar solvents. Chemically, they possess the properties of both monosaccharides (mutarotation, oxidation, reduction, ability to form glycosides) and hydroxy acids (formulation of esters and lactones). Uronic acids occur in nature with six carbon atoms, and their names are based on the corresponding hexose. The name “glucuronic acid,” for example, derives from “glucose.”

Uronic acids are constituents of many important biopolymers of plant and animal origin. D-glucuronic acid is a component of hemicelluloses, gums, hyaluronic acid, and heparin; D-galacturonic acid, which is the monomeric unit of pectic substances, is a constituent of certain bacterial polysaccharides. The biosynthesis of uronic acids occurs with the participation of nucleoside diphosphate sugars and involves the oxidation of the—CH2OH radical of the monosaccharide. In animals, D-glucuronic acid (found in the blood and urine) removes toxic substances by forming glycosides; the acid is also the starting material in the biosynthesis of absorbic acid.


Khimiia uglevodov. Moscow, 1967. Chapter 10.


References in periodicals archive ?
The contents of monosaccharides and uronic acids in the in the dietary fibre fractions from the kernels are presented in Table 3.
Thus; although, the reed contains a higher xylan concentration than eucalyptus, the uronic acids occur in lower quantities.
1] was related to C-O stretching vibrations with contributions from C-C stretching and C-C-O deformation vibrations of the uronic acids residues in heteropolymeric blocks.
The hydrolysate treated with sulphuric acid and uronic acid level was estimated in the presence of carbazole reagent with glucuronic acid lactone as standard (Bitter and Muir 1962).
Total dietary fibre determined as neutral sugar residues, uronic acid residues, and Klason lignin (The Uppsala Method): Collaborative study.
The QTLs were detected for fucose, galactose, and arabinose in our study; these monosaccharides with rhamnose and the uronic acids are primarily incorporated into pectic polysaccharides.
With increasing soil depth, the ratios of hexoses to pentoses as well as the concentrations of neutral sugars and uronic acids did not show a clear trend (Fig.
To account for one of the most important modes of detoxification in mammals, we measured uronic acid conjugates (principally glucuronic acid) in urine of woodrats from both populations.
Molecular design of a PET-based chemosensor for uronic acids and sialic acids utilizing a cooperative action of boronic acid and metal chelate.
In the SM of several oysters, hexosamines or hexoses and uronic acids are found in combination with sulfate (Crenshaw, 1972; Samata and Krampitz, 1982).
Fischer, "Ion-Pair RP-HPLC Determination of Sugars, Aminosugars and Uronic Acids after Derivatization with p-Aminobenzoic Acid," Anal.