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Inflammation of a blood vessel or a lymph vessel. Also known as angiitis.



inflammation of the walls of the small blood vessels. Vasculitis is usually caused by influenza, typhus, streptococcal infections (erysipelas, angina), or physical factors (frostbite, burns). Vasculitis may also arise as a secondary manifestation of collagen or allergic diseases, such as rheumatism, lupus erythematosus, rheumatoid arthritis, and serum and drug diseases. Sometimes vasculitis may be caused by a combination of some of these factors. The most usual, and often the only, external symptom of vasculitis is affection of the skin (hemorrhages, rashes, necrotic nidi, and so forth). As vasculitis progresses, thrombi may form in the vessels (thrombovasculitis), necrosis of the walls of the vessels may occur, and aneurysms may form. In the final stage of vasculitis complete occlusion of the vessels by a thrombus may occur, which leads to the disrupting of nutrition to the corresponding tissues and organs, bursting of aneurysms, and hemorrhaging into the surrounding tissues. Vasculitis is classified according to site as cutaneous and visceral; the latter predominantly affects the vessels of serous and mucous membranes of internal organs, such as the liver and kidneys. Treatment consists of the removal of the main disease causing the vasculitis.


Davydovskii, I. V. Patoligicheskaia anatomiia i patogenez boleznei cheloveka, 3rd ed., vols. 1-2. Moscow, 1956-58.


References in periodicals archive ?
In adults, the most common form of systemic vasculitis is giant cell arteritis (GCA)," says Dr.
Central nervous system vasculitis associated with hepatitis C virus infection: a brain MRI-supported diagnosis.
Abdominal pain in HSP is believed to be a result of vasculitis of the gastric, mesenteric, and/or colic vasculature.
Cutaneous vasculitis in primary SjAaAaAeA gren syndrome: Classificati and clinical significance of 52 patients.
The spectrum of paraneoplastic cutaneous vasculitis in a defined population: incidence and clinical features.
Keywords: Amyopathic dermatomyositis, interstitial lung disease, organising pneumonia, pulmonary vasculitis
Funders included the American College of Rheumatology, the European League Against Rheumatism, the Vasculitis Foundation, and the Dermatology Foundation.
Testing for specific ANCA, in the form of myeloperoxidase (MPO) and proteinase 3 (PR3) in the absence of positive IIF, rarely leads to the identification of patients with active vasculitis.
In this sense, our patient may be suffering from a MPO-ANCAassociated vasculitis with ENT and renal disease.
The literature mentions three mechanisms by which the nervous system may be affected, proposed by Drachman: 1) necrotizing vasculitis involving brain, spinal and radicular vessels; 2) contiguity extravascular granulomas in the paranasal sinuses, nasal cavities or orbits; 3) primary necrotizing granulomas in the skull, meninges, cranial nerves or brain (3,11,5).
Eosinophilic granulomatosis with polyangiitis (EGPA) is an autoimmune disorder characterized by necrotizing eosinophilic vasculitis of medium and small sized blood vessels.
2] The Chapel Hill Consensus Conference in 1994 defined PAN as 'necrotizing inflammation of medium sized or small arteries without glomerulonephritis or vasculitis in arterioles, capillaries or venules'.