Vesicular Stomatitis

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Related to Vesicular Stomatitis: Vesicular stomatitis virus

vesicular stomatitis

[ve‚sik·yə·lər ‚stō·mə′tīd·əs]
(veterinary medicine)
A viral disease, most often of horses, cattle, and pigs, characterized by fever and by vesicular and erosive lesions on the tongue, gums, lips, feet, and teats.

Stomatitis, Vesicular


an acute viral disease of animals manifested by fever and the formation of vesicles (blisters), mainly in the oral cavity. Vesicular stomatitis affects cattle, sol-idungulates, and swine. The disease occurs in several European and Asian countries; it usually occurs in humid weather during the period when animals pasture, which coincides with the season of activity of insects.

Infected animals are the source of vesicular stomatitis. The virus is transmitted by infected feed, water, milking machines, and workers who care for the animals. Horseflies, deerflies, mosquitoes, fungus gnats, crane flies, and the Phlebotomidae are mechanical transmitters of the disease. Vesicular stomatitis lasts one to three weeks, with the animals generally experiencing a complete recovery. Sick animals have a body temperature of 41–42°C, salivate profusely, and have no appetite. Besides the oral cavity, vesicles may also appear on the skin of other parts of the body.

Diagnosis is based on epizootiological and clinical findings and on laboratory tests. The disease is treated locally with antiinflammatories and antimicrobials. Preventive and control measures include the observance of health regulations, the isolation of sick animals, the disinfection of animal quarters, and the control of insects.


Krasnobaev, E. A. “Vezikuliarnyi stomatit.” In Laboratornaia dia-gnostika virusnykh boleznei zhivomykh. Moscow, 1972. Pages 70–80.
References in periodicals archive ?
Groups of African green monkeys (Chlorocebus aethiops) receiving recombinant vesicular stomatitis virus (rVSV) vaccine against Nipah virus Bangladesh strain ([NiV.sub.B]).
Ebert, "Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer," Cancer Research, vol.
Individual amplification of nucleic acids was performed for vesicular stomatitis, foot and mouth disease and contagious ecthyma.
Grasshoppers (Orthoptera: Acrididae) could serve as reservoirs and vectors of vesicular stomatitis virus.
Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein.
The cDNA and vector were rescued by transfecting the mouse cells with packaging vector and vesicular stomatitis virus G (VSV G).
In this experiment, the Murine Leukemia Virus (MLV) pseudotyped with the Vesicular Stomatitis Virus glycoprotein (VSVg) was used to transduce the NeoR and HygroR within a 293 cell line, human embryonic kidney cell line.
1993) for the animal pathogen vesicular stomatitis virus (VSV), a negative-sense, unsegmented RNA virus.
Through this agreement, IAVI obtained technology for a recombinant vesicular stomatitis virus (VSV) Lassa fever vaccine candidate, rVSV?G-LASV-GPC.
* Vesicular Stomatitis Virus-Based Vaccines against Lassa and Ebola Viruses

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