Dietrich joins Virion
with over 20 years of expertise in the manufacturing and development of vaccines and biopharmaceuticals.
A key aspect involves the replication of viral variants within the same host cell (as well as enveloping and variant occlusions) to form genetically heterogeneous occlusion-derived virions
and occlusion bodies (Clavijo et al.
Atabekov, "Translational cross-activation of Potexviruses virion
genomic RNAs," Acta Naturae, vol.
It has become routine to visualize the movement and progression of individual virions
in cells, but the relevance of these observations was previously unclear, as many virions
are defective or do not progress to make further copies of themselves.
Mastreviruses are monopartite, ssDNA viruses with ~2.5-2.7 kb circular genomes, encapsidated in twinned isometric viral particles but their genomes reported to express four proteins, encoded on the virion
and complementary strand equally (Boulton, 2002).
Chelico, "Mechanism of enhanced HIV restriction by virion
coencapsidated cytidine deaminases APOBEC3F and APOBEC3G," Journal of Virology, vol.
The mature flaviviral virion
is approximately 40 to 60 nm in diameter.
TEM observations showed that the derivative virions
of the inclusion bodies were rod-shaped and scattered within the inclusion bodies with an irregular arrangement.
Herpes virus virion
genes are replicated in a specific order (Figure 3): 8
penetrates the cell then makes use of the metabolic machinery and pathways of the living cell to make copies of its nucleic acid and synthesisze protein subunit.
Cilia, Gray, and their partners James Bruce and Juan Chavez of the University of Washington think that the outside shape, or topology, of the virion
plays a major role in that specificity, determining whether a virus will be able to move through the aphid and infect a plant.
The topics include the art and science of obtaining virion
stocks for experimental human papillomavirus infections, the structure and associations of E6 oncoproteins, the viral deregulation of DNA damage responses, the induction of genomic instability by human papillomavirus oncoproteins, and the role of the immune system in adenoviruses and gene therapy.