Walter Gilbert


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Gilbert, Walter,

1932–, American molecular biologist, b. Boston, Ph.D. Cambridge, 1957. In 1968 he became a professor of biophysics at Harvard, where he had taught since 1959. He helped formulate a method for determining the sequence of bases in nucleic acids (RNA and DNA) that made it possible to manufacture genetic material in the laboratory. For his role in this work, he shared the 1980 Nobel Prize in Chemistry with Frederick SangerSanger, Frederick
, 1918–2013, British biochemist, grad. Cambridge (B.A., 1939; Ph.D., 1943). He continued his research at Cambridge after 1943. He won the 1958 Nobel Prize in Chemistry for his studies on insulin, accomplishing the first determination of the amino acid
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 and Paul BergBerg, Paul,
1926–, American biologist, b. New York City, Ph.D. Western Reserve Univ., 1952. A professor at Washington Univ. at St. Louis and Stanford Univ., he shared the 1980 Nobel Prize in Physics (with Walter Gilbert and Frederick Sanger) for his work with recombinant
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.

Gilbert, Walter

(1932–  ) molecular biologist; born in Boston, Mass. He earned degrees in physics at Harvard and mathematics at Cambridge University, England. In his long career at Harvard (1959), he taught successively physics, biophysics, biochemistry, and molecular biology, and was named Carl M. Loeb university professor (1987). He identified the entire sequence of nucleotides in the DNA of a digestive protein produced by the E. coli bacterium (1977); the technique he developed (with Allan Maxam) for rapidly sequencing genes earned him a share of the Nobel Prize in chemistry (1980) and was critical in launching the new field of genetic engineering. In the 1980s he contributed to efforts to identify the basic components of proteins. He founded Biogen, a genetic engineering firm (1978; CEO 1981–84) and was a major force in launching the Human Genome Project in the late 1980s, designed to map all the genes on human chromosomes.
References in periodicals archive ?
He received the Nobel Prize in Chemistry in 1958 "for his work on the structure of proteins, especially that of insulin," and in 1980, he and Walter Gilbert shared the Nobel Prize in Chemistry "for their contributions concerning the determination of base sequences in nucleic acids" with Paul Berg who won "for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA."
Walter Gilbert (shown) coins the phrase "RNA world" for the early Earth environment in which RNA stored information and replicated itself.
Laura Furman Celia and Walter Gilbert Daniel Hall John Hollander Nicholas Howe and Georgina Kleege Anthony Hecht James Hoggard S.
Walter Gilbert, the successful biotechnology entrepreneur and well-known Nobel Prize-winning Professor at Harvard University.
Friedman, Massachusetts Institute of Technology, 1990-Physics; Walter Gilbert, Harvard University, 1980-Chemistry; Alfred G.
Leading biochemical scientists, including University of California at Berkeley retrovirus expert Peter Duesberg and Nobel Prize winner Walter Gilbert, have been warning for years that there is no proof that HIV causes AIDS.
The Nobel Prize in Chemistry was awarded jointly to Paul Berg of Stanford University for his studies of the manipulation of gene structures, and to Walter Gilbert of Harvard University and Frederick Sanger of England for their work on reading the fine details of the structure of DNA.
They competed against a team of scientists at the University of California, and a Harvard team led by Walter Gilbert, a former physicist who switched to molecular chemistry at the urging of Watson himself.
One of the world's first global biotechnology companies, Biogen was founded in 1978 by Charles Weissmann, Heinz Schaller, Kenneth Murray and Nobel Prize winners Walter Gilbert and Phillip Sharp, and today has the leading portfolio of medicines to treat multiple sclerosis, has introduced the first and only approved treatment for spinal muscular atrophy and is focused on advancing neuroscience research programs in Alzheimer's disease and dementia, multiple sclerosis and neuroimmunology, movement disorders, neuromuscular disorders, pain, ophthalmology, neuropsychiatry and acute neurology.
Founded in 1978 as one of the world's first global biotechnology companies by Charles Weissman and Nobel Prize winners Walter Gilbert and Phillip Sharp, Biogen has a portfolio of medicines to treat multiple sclerosis.