Wegener's granulomatosis


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

Wegener's granulomatosis

[′vā·gə·nərz ‚gran·yə·lə·mə′tō·səs]
(medicine)
A rare disease of unknown causation characterized by necrotizing granulomas in the air passages, necrotizing vasculitis, and glomerulitis.
References in periodicals archive ?
Neurological involvement in Wegener's granulomatosis: an analysis of 324 consecutive patients at the Mayo Clinic.
Mellemkjaer et al., "Malignancies in wegener's granulomatosis: incidence and relation to cyclophosphamide therapy in a cohort of 293 patients," The Journal of Rheumatology, vol.
Terayama et al., "P-ANCA-positive Wegener's granulomatosis presenting with hypertrophic pachymeningitis and multiple cranial neuropathies: Case report and review of literature," Neuropathology, vol.
Pusey, "Severe intestinal involvement in Wegener's granulomatosis," Gut, vol.
Savage, "Th2 dominance in nasal mucosa in patients with Wegener's granulomatosis," Clinical and Experimental Immunology, vol.
There are also reports of cases with neurological involvement in patients with refractory Wegener's granulomatosis treated with weekly injections of rituximab 375 mg / [m.sup.2] for 4 weeks and were able to achieve remission of the disease associated with the decline of ANCA titles and depletion of B cells in peripheral blood (9,17,12).
Salivary gland involvement in Wegener's granulomatosis. Arch Otolaryngol Head Neck Surg.
Merkel, "Epidemiology of Wegener's granulomatosis: lessons from descriptive studies and analyses of genetic and environmental risk determinants," Clinical and Experimental Rheumatology, vol.
Baslund, "Increased morbidity from ischemic heart disease in patients with Wegener's granulomatosis," Arthritis and Rheumatism, vol.
Holl-Ulrich et al., "Severe CNS manifestations as the clinical hallmark in generalized Wegener's granulomatosis consistently negative for antineutrophil cytoplasmic antibodies (ANCA).