Weil-Felix test


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Weil-Felix test

[′vīl ′fā·liks ‚test]
(immunology)
An agglutination test for various rickettsial infections based on production of nonspecific agglutinins in the blood of infected patients, and using various strains of Proteus vulgaris as antigen.
References in periodicals archive ?
(6-9) However, so many gold standard methods available but still many laboratories are using widely Weil-Felix test for the diagnosis of O.
Weil-Felix test and immunechromatographic tests, PCR and Anti O tsutsugamushi IgM and IgG based rapid diagnostic tests have been developed.
The Weil-Felix test was performed according to the manufacturer's instructions.
Selected patients met the following criteria: 1) fever (axillary temperature >37.5[degrees]C) for >15 days that did not respond to common antimicrobial drug therapy; 2) any additional clinical features including headache, rash, lymphadenopathy, myalgia, and eschars on skin; and 3) titer according to the Weil-Felix test (antibodies against any of 3 Proteus antigens) of >1:80.
Weil-Felix test was positive in high titres ([greater than or equal to] 1:320) and PCR for scrub typhus was also positive, which confirmed the diagnosis of scrub typhus.
The Weil-Felix test was used in the past as a presumptive test for the identification of rikettsiosis in routine laboratories, is based on the detection of antibodies to various Proteus species which contain antigens that cross-react against epitopes of members of the genus Rickettsia with the exception of R.
Blood and urine cultures, Widal test and Weil-Felix test were negative (1).
+A case is considered probable if testing reveals a fourfold rise in titer or a single titer -l :320 in the Weil-Felix test (OX-19 or OX-2) or an IHA, LA, or MA single titer of [greater than or equal to] 1:128.
ST rapid kits play a very crucial role in the early and specific diagnosis of ST, compared to the non-specific Weil-Felix test. Serious complications of ST are preventable by an early and accurate diagnosis followed by treatment.
Other diagnostic modalities include indirect fluorescent antibody test, Weil-Felix test, and immunochromatographic tests.
Serological response of patients suffering from primary and recrudescent typhus: comparison of complement fixation reaction, Weil-Felix test, microimmunofluorescence, and immunoblotting.