Weil-Felix test


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Weil-Felix test

[′vīl ′fā·liks ‚test]
(immunology)
An agglutination test for various rickettsial infections based on production of nonspecific agglutinins in the blood of infected patients, and using various strains of Proteus vulgaris as antigen.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
(6-9) However, so many gold standard methods available but still many laboratories are using widely Weil-Felix test for the diagnosis of O.
Weil-Felix test and immunechromatographic tests, PCR and Anti O tsutsugamushi IgM and IgG based rapid diagnostic tests have been developed.
The Weil-Felix test was performed according to the manufacturer's instructions.
Selected patients met the following criteria: 1) fever (axillary temperature >37.5[degrees]C) for >15 days that did not respond to common antimicrobial drug therapy; 2) any additional clinical features including headache, rash, lymphadenopathy, myalgia, and eschars on skin; and 3) titer according to the Weil-Felix test (antibodies against any of 3 Proteus antigens) of >1:80.
Weil-Felix test was positive in high titres ([greater than or equal to] 1:320) and PCR for scrub typhus was also positive, which confirmed the diagnosis of scrub typhus.
The Weil-Felix test was used in the past as a presumptive test for the identification of rikettsiosis in routine laboratories, is based on the detection of antibodies to various Proteus species which contain antigens that cross-react against epitopes of members of the genus Rickettsia with the exception of R.
Blood and urine cultures, Widal test and Weil-Felix test were negative (1).
+A case is considered probable if testing reveals a fourfold rise in titer or a single titer -l :320 in the Weil-Felix test (OX-19 or OX-2) or an IHA, LA, or MA single titer of [greater than or equal to] 1:128.
ST rapid kits play a very crucial role in the early and specific diagnosis of ST, compared to the non-specific Weil-Felix test. Serious complications of ST are preventable by an early and accurate diagnosis followed by treatment.
Other diagnostic modalities include indirect fluorescent antibody test, Weil-Felix test, and immunochromatographic tests.
Serological response of patients suffering from primary and recrudescent typhus: comparison of complement fixation reaction, Weil-Felix test, microimmunofluorescence, and immunoblotting.