Werner's syndrome


Also found in: Dictionary, Thesaurus, Medical.

Werner's syndrome

[′ver·nərz ‚sin‚drōm]
(medicine)
A complex of symptoms, thought to be inherited as an autosomal recessive, including premature senescence, dwarfism, cataracts, scleroderma-like changes of the skin, osteoporosis, and multiglandular dysfunction.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
DISCUSSION: Werner's syndrome is a rare autosomal recessive disorder.
Review of two siblings with Werner's syndrome. Case Report Med 2009: 2009; 1383-12
People with Werner's syndrome show signs of accelerated aging in their 20s, develop age-related diseases and generally die before age 50.
Werner's syndrome is the second form of Progeria and starts in adolescence or early adult life then follows the same rapid progression as the juvenile form.
Researchers have already gained much insight from the study of Werner's syndrome, a rare genetic disorder in which the normal aging clock is dramatically and disastrously accelerated.
Recent support for a central role of repair systems in ageing came from isolation of the gene for Werner's syndrome, a rare condition associated with premature ageing [21].
The impact of certain ancient genes on aging in humans can be seen in inherited aging diseases like Werner's syndrome. This is a type of disorder called a progeria, in which humans race through an aging-like process at a greatly accelerated pace.
Young people with Werner's syndrome acquire gray hair and diseases such as osteoporosis, cataracts, and hardening of the arteries.
Keywords: age-related disease, Cockayne's syndrome, Hutchinson-Gilford progeria, premature ageing syndromes, senescence-accelerated mouse, Werner's syndrome
Although there are real-life aging disorders, such as Progeria, Agrogeria and Werner's Syndrome, the ailment Jack suffers in the movie is invented.