Whipple's disease


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Related to Whipple's disease: tropical sprue, Whipple's procedure

Whipple's disease

[′wip·əlz di‚zēz]
(medicine)
A disease characterized by infiltration of the intestinal wall and lymphatics by macrophages filled with glycoprotein. Also known as intestinal lipodystrophy.
References in periodicals archive ?
After 42 years, the present name - Whipple's disease was introduced, when macrophages containing PAS--positive intracellular material were detected in autopsy or laparotomy (Periodic Acid Schiff staining).
Whipple's disease is a rare bacterial infection whose transmission has been unclear.
Granulomatous gastritis can appear in a number of clinical settings: Crohn's disease, sarcoidosis, infections, lymphoma, adenocarcinoma, Whipple's disease, Langerhans cell histiocytosis, gastric perforation, and vasculitis [1].
Value of Tropheryma whipplei quantitative polymerase chain reaction assay for the diagnosis of Whipple's disease: usefulness of saliva and stool specimens for first-line screening.
These include celiac disease, inflammatory bowel syndrome and Whipple's disease. Post mucosal causes arise due to those factors that hinder nutrient transport.
This paper aimed to report an atypical clinical manifestation of Whipple's disease with the formation of a lipophilic retroperitoneal tumour of reactive nature, simulating carcinomatosis.
Whipple called it intestinal lipodystrophy since he observed the accumulation of "large masses of neutral fats and fatty acids in the lymph spaces." The illness was renamed Whipple's disease in 1949 [3].
Crohn's disease was considered a possible cause of the presentation although the reporting radiologist suggested a differential diagnosis of Whipple's disease or giardiasis.
nih.gov/pubmed/) through April 2013, using the keywords "Tropheryma," "Whipple's disease," and "endocarditis." We then performed a cross-reference analysis on the results of the search.
Mycobacterium avium duodenal infection mimicking Whipple's disease in a patient with AIDS.
Lymphedema, lymphocytic myocarditis and sarcoidlike granulomatosis: manifestations of Whipple's disease. JAMA.