Different types of pediatric renal tumors are known, the commonest of which is Wilms tumor
or nephroblastoma, other less common tumors are nephroblastomatosis, rhabdoid malignant tumor, clear cell sarcoma, congenital mesoblastic nephroma and multilocular cystic nephroma3.
Van Tinteren et al., "Minimally invasive nephrectomy for Wilms tumors
in children--Data from SIOP 2001," Journal ofPediatric Surgery, vol.
Yoshioka, "The occurrence of Wilms tumor
in horseshoe kidneys: a report from the National Wilms Tumor
Study Group (NWTSG)," Journal of Pediatric Surgery, vol.
IHC study of Wilms tumors
(Figure 8) cases showed EMA, Vimentin (Figure 9), NSE and NF positivity.
Given its location and its classic small blue cell appearance, blastemal predominant Wilms tumor
should be high on the differential diagnosis.
Gain of 1q is associated with inferior event-free and overall survival in patients with favorable histology Wilms tumor
: A report from the Children's Oncology Group.
Preoperative Wilms tumor
rupture: A retrospective study of 57 patients.
The reductions in deaths paralleled changes in clinical practice, notably reductions in the use of cranial radiotherapy for patients with acute lymphoblastic leukemia from 86% of patients in the 1970s to 22% in the 1990s, as well as reductions in abdominal radiation given to children with Wilms tumor
(from 77% to 49%, respectively) and in chest radiation given for Hodgkin's lymphoma (from 96% to 77%).
When examined under a microscope, the tumors resemble immature embryonic kidneys, leading doctors to conclude that Wilms tumors
form when kidney development, normally complete by birth, persists into childhood.
Malignant rhabdoid tumor has been a somewhat controversial entity since it was first described in 1978 as a possible sarcomatous variant of Wilms tumor
. Eventually, however ...