(Provectus or the Company) is a clinical-stage biotechnology company developing a new class of drugs based on an entirely- and wholly-owned family of chemical small molecules called halogenated xanthenes
. Information about the Company's clinical trials can be found at the NIH registry, www.clinicaltrials.gov.
dyes are a family of compounds characterized by an intense absorption and fluorescence that has been widely employed for a variety of technological applications [1-5].
In order to understand the mechanisms involved in PDT, so that more effective photosensitizers can be developed, some synthetic xanthene
dyes have been considered.
Dorosz, "The xanthene
dyes doped PMMA microspheres for optical sensor applications," in Proceedings of the 16th Conference on Optical Fibers and Their Applications, Poland, September 2015.
The company added that the US patent covers use of certain halogenated xanthenes
in pharmaceutical compositions and as medicaments.
In order to furnish the versatility of this protocol, various types of aromatic aldehydes were used to synthesize corresponding xanthenes
and a benzophenone from Garcinia man gostana.
Presence of secondary metabolites like xanthenes
phenols quinonoids terpenoids and various flavonoids have previously been documented to inhibit snake venom enzymes.
Ghasemzadeh, "Zinc oxide nanoparticles: a highly efficient and readily recyclable catalyst for the synthesis of xanthenes
," Chinese Chemical Letters, vol.
Abdel-Mottaleb, "The interaction and photostability of some xanthenes
and selected azo sensitizing dyes with Ti[O.sub.2] nanoparticles," International Journal of Photoenergy, vol.
Utilizing a cross sectional study design, a convenience sample of prescriptions containing different combinations of ingredients such as corticosteroids, [beta.sub.2] agonists, xanthenes
, and cough and cold medications, were obtained from five pharmacies in Puerto Rico.
Depsides, depsidones, dibenzofuranes, xanthenes
, an thraquinones and usnic acids are amongst the more extensively studied lichen metabolites (Honda and Vilegas, 1998).