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city (1990 pop. 26,778), seat of Muskingum co., central Ohio, on the Muskingum River at its junction with the Licking River; inc. 1815. It is a trade and industrial center that manufactures metal products, machinery, glassware, and electrical equipment. The area has deposits of clay, oil, natural gas, sand, limestone, and iron ore. The rivers there, which are spanned by a notable "Y" bridge, are connected to the Ohio by 10 hand-operated locks and a 1-mi-long (1.6-km) canal.

The site was selected by Ebenezer ZaneZane, Ebenezer,
1747–1811, American pioneer and land speculator, b. near what is now Moorefield, W.Va. (then Virginia). With his brothers Silas and Jonathan, he went west in 1769 and established the settlement at Wheeling, of which he became the leader.
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, surveyor of Zane's Trace, the gateway to the Northwest TerritoryNorthwest Territory,
first possession of the United States, comprising the region known as the Old Northwest, S and W of the Great Lakes, NW of the Ohio River, and E of the Mississippi River, including the present states of Ohio, Ind., Ill., Mich., Wis., and part of Minn.
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. A two-year interval as state capital (1810–12) and the city's location on waterways and the National RoadNational Road,
U.S. highway built in the early 19th cent. At the time of its construction, the National Road was the most ambitious road-building project ever undertaken in the United States. It finally extended from Cumberland, Md., to St.
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 spurred its growth. An art institute and a campus of Ohio Univ. are in the city. Of interest are the National Road–Zane Grey museum, several early homes of Federal design, and the nearby Ohio Ceramic Center. A state park is at Dillon Reservoir to the northwest.

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References in periodicals archive ?
It was, one official said, 'like Noah's ark wrecking right here in Zanesville, Ohio."
"We're worried about another Zanesville, Ohio," said Katie Jarl, director of the Texas chapter of the Humane Society of the United States.
People in Zanesville, Ohio headed indoors as officers searched the countryside to hunt the animals that escaped from Muskingum County Animal Farm.
US police found Mr Thompson's body when they went to his farm after getting reports of creatures running free in Zanesville, Ohio, on Tuesday.
Born in Warren, Ohio and raised in Zanesville, Ohio, son of the late Robert P and Elizabeth (Knoedler) Axline, Sr, he lived in Northborough for the past 44 years.
That year the company made a momentous strategic decision, acquiring a drug distributor based in Zanesville, Ohio, and changing its name to Cardinal Distribution.
The commercial solar facility will be constructed on around 750 acres of reclaimed land once mined for coal in Noble County, 20 miles southeast of Zanesville, Ohio.
Also in full expansion mode, is relative industry newcomer Coll Materials Exchange LLC of Zanesville, Ohio. The firm opened its second recycling plant, in Waco, Texas, in April, and is expanding its headquarters plant in Zanesville.
Louis, Mo.; Belleville, Ill.: Vandalia, Ill.; Terre Haute, Ind.; Indianapolis, Ind.; Greenfield, Ind.; Dayton, Ohio; Columbus, Ohio; Zanesville, Ohio; Wheeling, Ohio; Morgantown, W.Va.; Frederick, Md.; Gaithersberg, Md.; Bethesda, Md.; and Washington, D.C.
From AAA (Anaa in French Polynesia) to ZZV (Zanesville, Ohio) we watch our luggage disappear, hoping someone recognises the difference between Aberdeen, South Dakota (ABR) and the Granite City (ABZ).
The top scholarships of $2,500 went to Adrian Sprankle of Zanesville, Ohio, and Brandi Waters of Brandenburg, Kentucky.
The Times Recorder of Zanesville, Ohio, has announced that Rick Szabrak has been named general manager of the Times Recorder and Coshocton Tribune, effective Monday.