Lin et al., "Determinants of metastatic rate and survival in patients with zollinger-ellison syndrome
: A Prospective Long-Term Study," Gastroenterology, vol.
The Zollinger-Ellison syndrome
: re-appraisal and evaluation of 260 registered cases.
usually occurs in people between ages 30 and 60.
(b) Patient had abnormal thickening of the interatrial septum and a history of Zollinger-Ellison syndrome
, so it is unclear whether this was an isolated case of conjunctival myxoma or associated with an underlying syndrome.
In clinical chemistry, the only well-indicated routine use of gastrin assays is in the diagnosis of gastrinomas, i.e., the Zollinger-Ellison syndrome
and NSAID use re responsible for some cases of peptic ulcer disease, but the vast majority are caused by Helicobacter pylori infection.
and NSAID use are responsible for some cases of peptic ulcer disease, but the vast majority are caused by Helicobacter pylori infection.
Two of the 143 patients developed gastric carcinoids during omeprazole treatment, which is consistent with the 1% historical incidence of this disease in patients with sporadic Zollinger-Ellison syndrome
, said Dr.
(The illness associated with these tumors is sometimes called Zollinger-Ellison syndrome
.) The ulcers caused by gastrinomas are much more dangerous than typical stomach or intestinal ulcers; left untreated, they can cause rupture of the stomach or intestine and even death.
(16-19,24,27,28) Later, a variety of endocrine syndromes including the Zollinger-Ellison syndrome
, carcinoid syndrome, multiple endocrine neoplasia type 1 syndrome, and Cushing syndrome were reported in association with ampullary carcinoids.
Patients were excluded if they had coexisting systemic disease affecting the esophagus, active gastrointestinal bleeding, Zollinger-Ellison syndrome
, esophageal varices, significant disease of major organs, abnormal laboratory values, current alcohol or illegal drug use, use of a PPI in the previous 3 months, or use of anticholinergic or prokinetic drugs during the screening period.
Also excluded were patients in whom esophagogastroduo-denoscopy could not be completed or a full series of biopsies obtained, as well as those with Zollinger-Ellison syndrome