tight junction

(redirected from Zonulae occludente)
Also found in: Medical.

tight junction

[¦tīt ′jəŋk·shən]
(cell and molecular biology)
An intercellular junction composed of a series of fusions of the junctional membrane, forming a continuous seal; serves as a selective barrier to small molecules and as a total barrier to large molecules. Also known as impermeable junction; occluding junction; zonula occludens.
References in periodicals archive ?
Also called zonulae occludentes, tight junctions are proteins found in gut linings and other places in the body.
For instance, when we retrieved the acronym ZO we had the following definitions: zonula occludens, zona occludens, zonulae occludentes. As one can see, these are either flexions of the same term (plural vs singular) or very close terms (zonula meaning 'small zone' vs zona).
Zonulae occludentes were deep ([tilde]22 fibrils), reflecting an electrically tight epithelium (732 ohms/[cm.sup.2]).