Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the Vps29, Vps30, and Vps35 gene products.
Park, Polycation gene delivery systems: escape from
endosomes to cytosol.
Following internalisation in an early
endosome, the toxin is transported to the Golgi apparatus then to the endoplasmic reticulum where the dissociated A subunit inhibits protein synthesis by destroying the function of ribosomal RNA (28S subunit).
The transfer between the circulation in the bloodstream and the
endosome and lysosome compartments (pH 5-6) was mimicked by a stepped release system.
Exosomes are vesicles of 30 to 100 nm in size originating in the
endosomes. Almost all cells release exosomes or extracellular vesicles (EVs) and are present in all body fluids.
Caption: Figure 2: SLC15A3 is located at lysosomes, late
endosome, and peroxisome.
toll-like receptors (TLRs) located on cell surface or in the
endosome, NLRs(NOD-like receptors) are cytoplasmic sensors and RLRs(RIG I-like receptors) recognize Viruses (Akira et al.,2006; Chen et al.,2009; Franchi et al.,2009).
RAB5B is a small GTPase that plays a role in early
endosome formation and is required for the endocytic pathway that mediates the transport of clathrin-coated vesicles from the plasma membrane to the early
endosome.