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nalidixic acid

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nalidixic acid

[¦nal·ə¦dik·sik ′as·əd]
(pharmacology)
C12H12N2O3 Pale buff, crystalline powder; melting point is 229-230°C; soluble in chloroform and in potassium hydroxide and sodium hydroxide solutions; used as an antibacterial drug in humans and animals.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive
coli isolated from dogs were susceptible to nalidixic acid and ciprofloxacin.
Occurrence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from domestic animals from Southern Ecuador/Ocorrencia e comportamento antimicrobiano de especies termotolerantes de Campylobacter isoladas de animais domesticos no sul do Equador
The numbering system of compounds from left to right is as follows: piroxicam (7), nalidixic acid (6), cinoxacin (8), difloxacin (3), enrofloxacin (10), pefloxacin (4), ofloxacin (1), lomefloxacin (9), ciprofloxacin (2), and pipemidic acid (5).
Isocratic Resolution of Fluoroquinolone-Based Antibiotics on the Phenylethyl-Bonded Phase under Nonaqueous Elution: A Consideration of the Separation Mechanism
pylori Using Nalidixic Acid and Cephalothin Antibiotics.
Isolation of Helicobacter pylori from Gastric Biopsy of Dyspeptic Patients in Ghana and In Vitro Preliminary Assessment of the Effect of Dissotis rotundifolia Extract on Its Growth
Resistance to nalidixic acid alone or in combination with other drugs was observed in 24% and 17.6% of isolates from eastern and central regions, respectively.
Phylogenetic Groups and Antimicrobial Susceptibility Patterns of Escherichia coli from Healthy Chicken in Eastern and Central Uganda
Evaluation of the current trend of Nalidixic Acid succeptibility in typhoidal Salmonella; a marker of therapeutic failure for the fluoroquionolones.
Synergistic Effect of Antibiotics against Bacterial Pathogens Causing Diarrhea Isolated from Children <5 Years of Age
[less than or 6-15 >15 equal to]5 Ampicillin 57 8 28 Trimothprim/ sulfamethoxazole 94 16 50 Nalidixic acid 98 17 46 Norfloxacin 64 11 30 Cefotaxime 5 0 5 Cefixime 9 0 8 [less than or 6-15 >15 equal to]5 Ampicillin 50 8 23 Trimothprim/ sulfamethoxazole 93 0 41 Nalidixic acid 88 18 40 Norfloxacin 16 4 10 Cefotaxime 10 3 3 Cefixime 8 2 3 Note: Table made from bar graph.
Molecular characterization of antimicrobial resistance in clinical Shigella isolates during 2014 and 2015: trends in South India
Overall resistance to FQs tested was almost similar: moxifloxacin (74.4%) ciprofloxacin (79.3%), sparfloxacin (80.1%), ofloxacin (80.3%), norfloxacin (80.9%) and enoxacin (81.8%) with greater resistance to nalidixic acid (91.7%).
Antibiotics susceptibility patterns of uropathogenic E. coli with special reference to fluoroquinolones in different age and gender groups
Nalidixic acid have maximum of all biological activities, but H-6 showed slightly better antioxidant activity than Nalidixic acid and other activities were close to it.
Synthesis, Spectroscopic Characterizations, and Biological Evalution of Some Substituted 1-Ethyl-1,4-Dihydro-7-Methyl-4-Oxo-1,8-Naphthyridine-3-Carbohydrazide and their Copper Complexes
In vitro antibacterial activity of AM-715, a new nalidixic acid analog.
Fluoroquinolone [floor"o-kwm'o-lon]
There were intermittent zones of inhibition to the claforan, nalidixic acid, amoxycillin, fosfomycin, fortum, and erythromycin (Table 3).
Epidemiological Studies of Potent Environmental Pathogen: Streptococcus pneumoniae
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