Amination

amination

[‚am·ə′nā·shən]

(organic chemistry)

The preparation of amines.

A process in which the amino group (=NH₂) is introduced into organic molecules.

McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Amination

 

a method of introducting the amino group NH₂ into various organic compounds. A typical example of amination is the action of alkali metal amides on heterocyclic bases. Thus, the interaction of pyridine with sodium amide at temperatures of about 200°C leads to the formation of α-aminopyridine (A. E. Chichibabin and O. A. Zeide, 1914):

C₅H₅N + NaNH₂ → C₅H₄N(NH₂) + NaH

Passing benzene vapor with ammonia through an incandescent tube results in a very low output of aniline:

C₆H₆ + NH₃ → C₆H₅NH₂ + H₂

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.