abasia

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abasia

[ā′bā·zhə]
(medicine)
Lack of muscular coordination in walking.
References in periodicals archive ?
Friedberg, "Inhibition of Rad3 DNA helicase activity by DNA adducts and abasic sites: implications for the role of a DNA helicase in damage-specific incision of DNA," Biochemistry, vol.
From the black awning and faAs.ade to the black tablecloths, partly black wall space and dark furnishings, it presents itself in the manner of abasic blacka elegance.
A method for detecting abasic sites in living cells: Age-dependent changes in base excision repair.
CORONATION STREET ABASIC rule, constantly broken in soapland, is to have a look around you when you're discussing a big secret.
Induction of abasic sites by the drinking-water mutagen MX in Salmonella TA100.
The oxidatively induced DNA damage associated with ROS is apurinic or apyrimidinic (abasic) DNA sites, oxidized purines and pyrimidines, and single- and double-strand DNA breaks.
ROS-related oxidation of DNA is one of the main causes of mutations, such as nonbulky (8-oxoguanine and formamidopyrimidine) and bulky (cyclopurine and etheno adducts) base modifications, abasic sites, nonconventional single-strand breaks, protein-DNA adducts, and intra- or interstrand DNA crosslinks [9].
This pathway entails removal of the damaged bases and resulting abasic region, followed by insertion of the correct nucleotides and ligation to seal the gap (Lu et al.
Company guidance from the 1Q11 results conference call remains intact with a FY11 bottom line of RUB1.1bn seen as a abasic and conservative forecasta with upside of RUB1.5bn purely on tax effects.
Descriptively, the hOGG1 gene on chromosome 3p26 catalyzes the cleavage of a glycosylic bond between the modified base and a sugar moiety, leaving an abasic apurinic/apyrimidinic site in DNA which is then incised followed by a few successive actions of a phosphodiesterase that completes the repair process with a final function by a DNA polymerase, and a DNA ligase (7,8).
BIRMINGHAM Mail OurSay ABASIC requirement for any sort of stable life is to have a secure roof over your head.
A novel fluorometric oligonucleotide assay to measure O(6)-methylguanine DNA methyltransferase, methylpurine DNA glycosylase, 8-oxoguanine DNA glycosylase and abasic endonuclease activities: DNA repair status in human breast carcinoma cells overexpressing methylpurine DNA glycosylase.