These features suggested the diagnosis of acanthomatous ameloblastoma. IHC Ki-67 also showed mild positivity in fewer areas (Figure 5).
Acanthomatous ameloblastoma accounts for the third most common histological variant of ameloblastoma .
Canine acanthomatous ameloblastoma
(CAA) or acanthomatous epulis is a benign oral tumor of dogs and cats with locally invasive behavior.
(13.) Brooks JK, Al-Mubarak H, Ribera MJ, Cohen PD, Ross DS, ScheperMA.Diminutive, interradicular "hybrid" desmoplastic/ acanthomatous ameloblastoma. Quintessence Int.
(8,16) The present case was diagnosed as a hybrid ameloblastoma according to the diagnostic criteria established by Waldron and El-Mofty (10) as it showed histopathological features of the desmoplastic variant along with other variants like follicular, cystic, and acanthomatous ameloblastomas. This finding confirmed a unique hybrid variant, which we herewith report as the first of its kind to the best of our knowledge.
Acanthomatous ameloblastoma in a dog: a case report
Radiation therapy for oral tumors: Canine acanthomatous ameloblastoma. Can Vet 2007; 48(1): 99-101.
Krishna et al studied protein over expression (MDM2) in ameloblastoma and oral squamous cell carcinoma (OSCC) and found that the keratinizing cells of acanthomatous ameloblastoma
showed less MDM2 reactivity as compared to high reactivity in OSCC which could be suggestive of terminal differentiation and non-proliferative phenotype of central cells.
is a rare variant of follicular ameloblastoma with squamous metaplasia and even keratinization are seen in the stellate reticulum area.