The lesion is acanthotic
and hyperkeratotic with variable degree of papillomatosis and/ or invagination (Figure 8, A).
--Most oral precancerous lesions show hyperkeratosis and acanthosis, dysplastic lesions may be atrophic as well as acanthotic
Histiocytes and lymphocytes surrounded superficial dermal blood vessels, and the epidermis appeared to be acanthotic
with orthokeratotic hyperkeratosis as well as a focal area of superficial ulceration of the keratin layer.
Microscopically, the tumor consisted of well-differentiated acanthotic
squamous mucosa with bland cytologic features growing in a verrucous pattern (Figures 4a & 4b) and many areas showing broad pushing borders.
Biopsies of the hyperpigmented areas revealed an acanthotic
, parakeratotic and hyperkeratotic squamous epithelium with hyperpigmentation of the basal layer of the epithelium with increased number of melanocytes (Fig.
Histologic analysis of a DF reveals an acanthotic
epidermis with a proliferation of spindle cells in the mid and lower dermis, with capillaries dispersed throughout.
The skin biopsies revealed discrete acanthotic
epidermis with focal areas showing mononuclear cell exocytosis.
The epidermis surrounding the crater is acanthotic
Hematoxylin-eosin-stained sections demonstrate a polypoid fragment of skin with a slightly acanthotic
epidermis with overlying hyperkeratosis (Figure 2, A).
The lesion is composed of squamous epithelium which usually present with acanthotic
psoriasiform hyperplasia in the epithelium and is sharply demarcated from the lateral border [Figure 3].
Histological examination of the specimen revealed parakeratosis with uniformly acanthotic
epidermis (Figure 2).
Histological examination showed an acanthotic
epidermal pattern with a compact keratin layer, and enlarged clear cells with perinuclear vacuolization in the superficial squamous layer.