The lesion is
acanthotic and hyperkeratotic with variable degree of papillomatosis and/ or invagination (Figure 8, A).
--Most oral precancerous lesions show hyperkeratosis and acanthosis, dysplastic lesions may be atrophic as well as
acanthotic (57,58,59)
Histiocytes and lymphocytes surrounded superficial dermal blood vessels, and the epidermis appeared to be
acanthotic with orthokeratotic hyperkeratosis as well as a focal area of superficial ulceration of the keratin layer.
Microscopically, the tumor consisted of well-differentiated
acanthotic squamous mucosa with bland cytologic features growing in a verrucous pattern (Figures 4a & 4b) and many areas showing broad pushing borders.
Biopsies of the hyperpigmented areas revealed an
acanthotic, parakeratotic and hyperkeratotic squamous epithelium with hyperpigmentation of the basal layer of the epithelium with increased number of melanocytes (Fig.
Histologic analysis of a DF reveals an
acanthotic epidermis with a proliferation of spindle cells in the mid and lower dermis, with capillaries dispersed throughout.
The skin biopsies revealed discrete
acanthotic epidermis with focal areas showing mononuclear cell exocytosis.
The epidermis surrounding the crater is
acanthotic with hyperkeratosis.
Hematoxylin-eosin-stained sections demonstrate a polypoid fragment of skin with a slightly
acanthotic epidermis with overlying hyperkeratosis (Figure 2, A).
The lesion is composed of squamous epithelium which usually present with
acanthotic psoriasiform hyperplasia in the epithelium and is sharply demarcated from the lateral border [Figure 3].
Histological examination of the specimen revealed parakeratosis with uniformly
acanthotic epidermis (Figure 2).
Histological examination showed an
acanthotic epidermal pattern with a compact keratin layer, and enlarged clear cells with perinuclear vacuolization in the superficial squamous layer.