"Derivatives of 4-hydroxycoumarin (including warfarin and acenocoumarol
) specifically inhibit VKOR, thus preventing the recycling of vitamin K."
Reliability of thromboelastometry for detecting the safe coagulation threshold in patients taking acenocoumarol
after elective heart valve replacement.
In our patient, the anticoagulant treatment was initiated with LMWH, and continued with VKA (acenocoumarol
therapy was discontinued and instead low molecular weight heparin therapy was started, still maintained today.
(3,4) Similarly, multiple studies suggest warfarin-related nephropathylike syndromes occurring with other anticoagulants, such as acenocoumarol
(5,6) and dabigatran.
Due to pulmonary embolism in the past, the patient was treated with acenocoumarol
. Additionally, diltiazem, fraxiparine, iron preparations i.v.
Safety and effectiveness of low dose oral vitamin K1 administration in asymptomatic out-patients on warfarin or acenocoumarol
with excessive anticoagulation.
Mittal, "CYP4F2 1347 G> A & GGCX 12970 C> G polymorphisms: frequency in north Indians & their effect on dosing of acenocoumarol
oral anticoagulant," The Indian Journal of Medical Research, vol.
Treatment with OACs accounts for approximately 20% of all cases of ICH, most of which are associated with the vitamin K antagonists (VKAs), acenocoumarol
and warfarin .
Her medical history included incidents of superficial-vein thrombosis in 2005, 2008, and 2009 (with negative family history of thrombosis) for which she was receiving acenocoumarol
. Since the confirmation of pregnancy she was receiving Salospir 100 mg p.o.
Medications at home were clopidogrel, acenocoumarol
, oral amiodarone, a b-blocker, and a calcium-channel blocker, but it was unclear if these were taken as instructed.