acetoacetic acid


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Related to acetoacetic acid: Ketone bodies, acetoacetic ester

acetoacetic acid

[¦as·ə‚tō‚ə′sēd·ik ′as·əd]
(organic chemistry)
CH3COCH2COOH A colorless liquid miscible with water; derived from β-hydroxybutyric acid in the body.
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M/Z RT VIP Formula 97.9769 753.0 0.218203 [H.sub.3]P[O.sub.4] 165.0790 521.4 0.287885 [C.sub.9][H.sub.11]N[O.sub.2] 102.0317 876.0 0.309992 [C.sub.4][H.sub.6][O.sub.3] 203.0252 1789.8 0.312836 [C.sub.7][H.sub.9]N[O.sub.4]S M/Z Metabolites 97.9769 Phosphoric acid 165.0790 L-Phenylalanine 102.0317 Acetoacetic acid 203.0252 Cystathionine ketimine Table 9: Metabolic pathways involved in parts of the same metabo- lites from serums of patients with CHD and CRF showing dampness syndrome.
Fat metabolism results in the accumulation of beta-hydroxybutyric (B-OH) acid and acetoacetic acid. These two acids are the keto-acids.
Therefore, if the presence of a slight but definite purple color that appeared less than the "small color block" was reported as negative, the presence of acetoacetic acid at detectable levels would be unreported.
The hydratase deficiency in these patients was identified by use of a radioactive enzyme assay measuring three consecutive steps of leucine degradation, from 3-methylcrotonyl-CoA to acetoacetic acid (12).