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A condition of decreased alkali reserve of the blood and other body fluids.



a change in the acid-alkaline balance of the organism as a result of insufficient removal and oxidation of organic acids (for example, beta-hydroxybutyric acid). Usually these products are rapidly removed from the body. In febrile diseases, intestinal disorders, pregnancy, starvation, and such, they are retained in the body; this is manifested in mild cases by the appearance of acetoacetic acid and acetone in the urine (so-called ketonuria). In severe cases (for example, diabetes mellitus) it may lead to coma. Treatment consists of removal of the cause of acidosis (for example, by administering insulin in case of diabetes); there is also symptomatic treatment—soda and an abundance of fluids taken internally.

References in periodicals archive ?
The effect of temperature and pH on the activity of factor Vila: implications for the efficacy of high-dose factor Vila in hypothermic and acidotic patients.
This study has identified that patients who are acidotic, hypoxic and requiring inotrope infusions on arrival in the ICU are at particularly high risk of also having a higher postoperative MPAP.
She became acidotic and hypotensive (systolic BP in the 80s) and required aggressive management with multiple intravenous inotropes and vasopressors including dopamine, dobutamine, and norepinephrine (phenylephrine).
A glut might lead to higher representation in stimulating turnover, and in constituting a high protein diet; although the acidotic (and potentially bone resorptive) effects of a high protein diet have also been cited (Parkington 1991).
In addition, hypoxic and acidotic conditions were absent in nonsubmerged control turtles which did not experience substantial shifts in plasma ion concentrations, osmotic pressure, or hematocrit.
et al, in regards to zeta-crystallin and glutaminase interactions and expression of the glutaminase(GA) mRNA, under conditions mimicking normal and acidotic physiology's.
Preliminary results indicate the presence of NHE-like proteins in the mum-michog (Fundulus heteroclitus) and that there is an upregulation of NHE-1-like proteins under acidotic conditions in the gills of seawater adapted mummichogs, while no differences in expression could be quantifi ed in freshwater adapted fish.
They are commercially prepared by adjusting acidity to simulate acidotic, alkalotic, and normal specimens.
In previously published work, Arieff and his colleagues compared the effects of sodium bicarbonate, sodium chloride and no treatment in dogs made acidotic by limiting their oxygen intake.
Although no human data are available, electrolyte imbalance, development of an acidotic state, and possible central nervous system effects may occur.
Clinical and laboratory criteria for severe malaria (any one or combination of these criteria applies) Clinical Impaired consciousness, multiple convulsions Respiratory distress, acidotic breathing, pulmonary oedema Circulatory collapse Jaundice Bleeding Prostration Laboratory Hypoglycaemia (blood glucose <2.
The diet in our study containing a high proportion grain was rich in rapidly fermentable carbohydrates, resulting in the decrease in the rumen pH to acidotic values, with the rumen fluid pH being below 5.