acinar


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acinar

[′as·ə·nər]
(anatomy)
Pertaining to an acinus.
References in periodicals archive ?
Immunohisto-chemically solid pseudopapillary tumor of pancreas can show overlapping expression of pan CK, synaptophysin, CD56, chromogranin, CD10 and vimentin with neuroendocrine tumors19,20, the expression of neuroendocrine markers with pancreatoblastoma and pancreatic enzymes with acinar cell carcinoma18.
Sections showed neoplastic epithelial cells arranged in trabeculae or clusters, with frequent acinar structures.
In the present study, edema, acinar necrosis, hemorrhage, fat necrosis, and inflammation in pancreas was evaluated according to the histopathological scoring scale defined by Lowry et al.
98) In addition, various mutations of the pancreatitisassociated gene, serine protease inhibitor, Kazal type I (SPINK1) gene (the gene encoding an inhibitor of activated trypsin) impairs negative regulation of trypsinogen activation occurring in acinar cells.
Atypical small acinar proliferation reflects a broad group of prostate lesions with insufficient changes in the cells to definitively diagnose prostate cancer.
14] AMACR is also a useful diagnostic marker for the adenocarcinoma variants like foamy gland and pseudohyperplastic prostate carcinoma, although positivity is lower than that in acinar adenocarcinoma.
More recently, studies have turned to determining effects of alcohol on the pancreatic duct cell, which is important for producing fluid secretion and carrying digestive enzymes secreted by the acinar cell into the gut lumen, where they are needed for meal digestion.
The severity of acute pancreatitis was blindly graded by a semiquantitative assessment of edema, inflammatory cell infiltrate, and acinar necrosis, based on the following criteria: (1) edema: 0 = absent, 1 = focally increased between lobules, 2 = diffusely increased between lobules, and 3 = acini disrupted and separated; (2) inflammatory cell infiltration: 0 = absent, 1 = rare or around ductal margins, 2 = in the parenchyma (<50% of the lobules), and 3 = in the parenchyma (>50% of the lobules); (3) necrosis: 0 = absent, 1 = architectural changes, 2 = pycnotic nuclei, 3 = focal necrosis (<10% of the parenchyma), and 4 = diffuse parenchymal necrosis (>10% of the parenchyma).
Caption: Figure 5: Adenocarcinoma component with acinar growth pattern (H&E x10 objective).
The majority of prostate cancers are acinar adenocarcinomas.