acinar cell


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Related to acinar cell: Acinar cell carcinoma

acinar cell

[′as·ə·nər ′sel]
(anatomy)
Any of the cells lining an acinous gland.
References in periodicals archive ?
Development of pancreatic acinar cell metaplasia after successful administration of omeprazole for 6 months in rats.
Histopathological examination of hematoxylin and eosin stained sections revealed an encapsulated tissue (figure 4) composed of numerous serous acinar cells with abundant granular basophilic cytoplasm and round darkly stained eccentrically placed nucleus with multiple vacuolated cyst-like spaces (figure 5).
Miura et al., "Xanthine oxidase-mediated in response to cerulein in intracellular oxidative stress rat pancreatic acinar cells," Pancreas, vol.
Although increased proliferation of pancreatic acinar cells could be measured by the method of BrdU incorporation, the effects of THs on pancreatic cancer showed to be bidirectional by now according to the reports and the mechanism had been just partly explored.
(38) Finally, it should be noted that parenchymal cells such as hepatocytes (39) and pancreatic acinar cells express functional NOD1; (12-14) in the latter case, sensing of commensal organism-derived PGN by NOD1 mediates acute and chronic pancreatitis as discussed in greater detail below.
There has been increasing evidence that the nonoxidative pathway plays an important role in alcohol pathogenesis in the acinar cell. For example, FAEEs were found to cause necrosis in pancreatic acinar cells by inducing sustained increases in free concentrations of [Ca.sup.2+] in the cytoplasm from released intracellular stores, leading to toxicity of mitochondria and failure to produce ATP (Criddle et al.
The pancreas is composed of endocrine cells ([alpha]-cells, [beta]-cells, etc.), acinar cells, and ductal cells, which all derive from a common progenitor expressing Pdx1 [43].
According to histological injury scores, the score severity of the pancreatic injury could be reflected by the scores of edema, acinar cell necrosis, hemorrhage, inflammation, and perivascular infiltration.
Pancreatic acinar cell carcinoma is a rare neoplasm, representing 1% to 2% of exocrine pancreatic neoplasms in adults [2].
The multidirectional differentiation of the neoplastic cells together with a scarcity in morphological hallmark of serous acinar cell differentiation, as evidenced in some cases, poses a real diagnostic challenge.